You are viewing an incomplete version of our website. Please click to reload the website as full version.

Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) antibody

Details for Product No. ABIN1107048, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

(94), (31), (31), (4), (1), (1)
(67), (20), (7)
Clonality (Clone)
Monoclonal ()
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(63), (47), (24), (12), (11), (4), (2), (2), (1), (1), (1)
Pubmed 3 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Human uterine cervical adenocarcinoma cell
Clone 22-01-01
Isotype IgM
Specificity This antibody recognizes RCAS1.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein-L Sepharose
Alternative Name EBAG9 / RCAS1 (EBAG9 Antibody Abstract)
Background RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) is a novel tumoreassociated antigen expressed in human uterine and ovarian carcinomas. The predicted amino acid sequence of RCAS1 (213 a.a.) possesses an N-terminal transmembrane region and a coiled-coil structure in the C-terminal portion, indicating that RCAS1 is a type II membrane protein able to form oligomers through the coiled-coil structure. RCAS1 revealed different expression pattern from the known tumore associated antigens such as, YH206, GA733, CA125, CEA and sialyl Le molecules in human tumore cell lines. Recent study indicated RCAS1 acts as a ligand for a putative receptor present on various human cells including T, B and NK cells. RCAS1 inhibited the in vitro growth of receptor-expressing cells and induced apoptosis. It was suggested that tumore cells might evade immune surveillance by expression of RCAS1.Synonyms: Cancer-associated surface antigen RCAS1, EB9, Estrogen receptor-binding fragment-associated gene 9 protein, PDAF, Receptor-binding cancer antigen expressed on SiSo cells
Gene ID 9166
NCBI Accession NP_004206
UniProt O00559
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer 100 μg IgG in 100 μLvolukme of PBS containing 50 % glycerol and 0.5 M NaCl, pH 7.2 No preservative is contained.
Preservative Azide free
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) antibody (ABIN1107048) IHC on human uterine cervical adenocarcinoma
Background publications Wicherek, Dutsch, Mak et al.: "Comparative analysis of RCAS1 level in neoplasms and placenta." in: Acta biochimica Polonica, Vol. 50, Issue 4, pp. 1187-94, 2004 (PubMed).

Nakashima, Sonoda, Watanabe: "Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1." in: Nature medicine, Vol. 5, Issue 8, pp. 938-42, 1999 (PubMed).

Sonoda, Kaku, Kamura et al.: "Tumor-associated antigen 22-1-1 expression in the uterine cervical squamous neoplasias." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 4, Issue 6, pp. 1517-20, 1998 (PubMed).

Catalog No. ABIN1107048
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)