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Osteoprotegerin antibody (N-Term)
TNFRSF11B
Reactivity: Human
WB, EIA
Host: Mouse
Monoclonal
OPG-13
unconjugated
Product Details anti-Osteoprotegerin Antibody
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Target
See all Osteoprotegerin (TNFRSF11B) Antibodies
Osteoprotegerin (TNFRSF11B)
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Binding Specificity
All epitopes for Osteoprotegerin antibodies
AA 21-39, N-Term
Reactivity
All reactivities for Osteoprotegerin antibodies
Human
Host
All hosts for Osteoprotegerin antibodies
Mouse
Clonality
All clonalities for Osteoprotegerin antibodies
Monoclonal
Conjugate
All conjugates for Osteoprotegerin antibodies
This Osteoprotegerin antibody is un-conjugated
Application
All applications for Osteoprotegerin antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
The Anti Human Osteoprotegerin, Clone: OPG-13 is a mouse monoclonal antibody against synthetic peptide of Human Osteoprotegerin.
Purification
Affinity chromatography on protein G
Immunogen
Synthetic OPG peptide that comprises AA21 to AA39 homologous with human osteoprotegerin (N-terminal C has been added to the peptide)
Clone
OPG-13
Isotype
IgG1
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Discover our top product TNFRSF11B Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Reconstitution
Restore with 0.1 mL of deionized water
Concentration
1.0 mg/mL
Buffer
0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
Preservative
Azide free
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
Expiry Date
6 months
Target Details for Osteoprotegerin
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Target
Osteoprotegerin (TNFRSF11B)
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Alternative Name
Osteoprotegerin / TNFRSF11B (TNFRSF11B Products )
Synonyms
CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, OCIF antibody, OPG antibody, TR1 antibody, Opg antibody, ocif antibody, opg antibody, tr1 antibody, TNF superfamily member 11 antibody, TNF receptor superfamily member 11b antibody, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antibody, TNF receptor superfamily member 11B antibody, tumor necrosis factor receptor superfamily member 11b S homeolog antibody, tumor necrosis factor receptor superfamily, member 11b antibody, TNFSF11 antibody, TNFRSF11B antibody, Tnfrsf11b antibody, tnfrsf11b.S antibody
Target Type
Chemical
Background
Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues, it has a molecular weight of 60 kDa as a monomer and 120 kDa as a disulfide-linked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. Osteoprotegerin inhibits the recruitment, proliferation and activation of osteoclasts. Osteoclast formation activity may be monitored principally by determination of concentration ratio of osteoprotegerin ligand (OPGL)/OPG. Alteration of this ratio may be the cause of bone loss in many imbalances in bone metabolism such as osteoporosis, osteopetrosis, hypercalcemia, metastatic osteolytic lesions and rheumatic bone degradation.Synonyms: OCIF, OPG, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
Gene ID
4982
NCBI Accession
NP_002537
UniProt
O00300
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