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Osteoprotegerin Products

(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))

Categories

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].

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Featured Osteoprotegerin Categories

Osteoprotegerin Antibodies

High quality antibodies with extensive validation data.

Osteoprotegerin ELISA Kits

Reliable ELISA kits for a wide range of species.

Osteoprotegerin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Osteoprotegerin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (7)
Cat. No. ABIN3022915
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7431044
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7431047
Quantity 100 μL
Datasheet Datasheet

Recommended Osteoprotegerin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (17)
  • (1)
Cat. No. ABIN6960288
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6960286
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (9)
  • (1)
Cat. No. ABIN6960285
Quantity 96 tests
Datasheet Datasheet

Recommended Osteoprotegerin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275758
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275769
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN1323154
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our Osteoprotegerin products

Hendrijantini, Suisan, Megantara, Tumali, Kuntjoro, Ari, Sitalaksmi, Hong: "Bone Remodeling in Mandible of Wistar Rats with Diabetes Mellitus and Osteoporosis." in: European journal of dentistry, (2022) (PubMed).

Häussling, Aspera-Werz, Rinderknecht, Springer, Arnscheidt, Menger, Histing, Nussler, Ehnert: "3D Environment Is Required In Vitro to Demonstrate Altered Bone Metabolism Characteristic for Type 2 Diabetics." in: International journal of molecular sciences, Vol. 22, Issue 6, (2021) (PubMed).

Manglani, Vijayan, Pathak, Khandelwal, Singh, Chellappa, Yadav, Surolia, Gupta: "Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process." in: Bone, Vol. 122, pp. 123-135, (2020) (PubMed).

Pei, Chen, Zhou, Min, Xiao: "IL-38 restrains inflammatory response of collagen-induced arthritis in rats via SIRT1/HIF-1α signaling pathway." in: Bioscience reports, Vol. 40, Issue 5, (2020) (PubMed).

Du, Yan, Zhu, Chen, Wang, Ye, Wang, Zhu, Lu, Cao: "QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism." in: Cell death & disease, Vol. 11, Issue 5, pp. 330, (2020) (PubMed).

Pezhman, Sheikhzadeh Hesari, Ghiasi, Alipour: "The impact of forced swimming on expression of RANKL and OPG in a type 2 diabetes mellitus rat model." in: Archives of physiology and biochemistry, Vol. 125, Issue 3, pp. 195-200, (2019) (PubMed).

Jayusman, Mohamed, Alias, Mohamed, Shuid: "The Effects of Quassinoid-Rich Eurycoma longifolia Extract on Bone Turnover and Histomorphometry Indices in the Androgen-Deficient Osteoporosis Rat Model." in: Nutrients, Vol. 10, Issue 7, (2019) (PubMed).

Gegen, Zhu, Sun, Hou: "Role of interleukin-33 in the clinical pathogenesis of chronic apical periodontitis." in: The Journal of international medical research, Vol. 47, Issue 7, pp. 3332-3343, (2019) (PubMed).

Wang, Cao, Liu, Wang, Chu, Wang, Hu, Zhao, Diao, Peng, Ye, Cao: "Alveolar Bone Density Reduction in Rats Caused by Unilateral Nasal Obstruction" in: Balkan medical journal, Vol. 36, Issue 6, pp. 311-319, (2019) (PubMed).

Lee, Chan, Hsieh, Lew, Feng: "Comparing the Osteogenic Potentials and Bone Regeneration Capacities of Bone Marrow and Dental Pulp Mesenchymal Stem Cells in a Rabbit Calvarial Bone Defect Model." in: International journal of molecular sciences, Vol. 20, Issue 20, (2019) (PubMed).

Synonyms and alternative names related to Osteoprotegerin

TNF superfamily member 11 (TNFSF11), TNF receptor superfamily member 11b (TNFRSF11B), tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b), TNF receptor superfamily member 11B (Tnfrsf11b), tumor necrosis factor receptor superfamily member 11b S homeolog (tnfrsf11b.S), tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B), CD254, hRANKL2, OCIF, ocif, ODF, OPG, Opg, opg, OPGL, OPTB2, RANKL, sOdf, TR1, tr1, TRANCE

Protein level used designations for Osteoprotegerin

  • TNF-related activation-induced cytokine
  • osteoclast differentiation factor
  • osteoprotegerin ligand
  • receptor activator of nuclear factor kappa B ligand
  • receptor activator of nuclear factor kappa-B ligand
  • tumor necrosis factor ligand superfamily member 11
  • osteoclastogenesis inhibitory factor
  • osteoprotegerin
  • tumor necrosis factor receptor superfamily member 11B
  • Osteoprotegerin
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
  • tumor necrosis factor receptor superfamily, member 11b
  • tumor necrosis factor receptor superfamily member 11B-like
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