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AMACR antibody

AMACR Reactivity: Human IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN115447
  • Target See all AMACR Antibodies
    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
    Reactivity
    • 102
    • 17
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 65
    • 37
    • 2
    Rabbit
    Clonality
    • 52
    • 52
    Polyclonal
    Conjugate
    • 63
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AMACR antibody is un-conjugated
    Application
    • 69
    • 51
    • 38
    • 34
    • 18
    • 18
    • 11
    • 11
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Reacts to P504S Alpha-Methylacyl-CoA Racemace.
    Cellular Localization: Cytoplasmic.
    Purification
    Purified
    Immunogen
    A synthetic human AMACR peptide.
    Top Product
    Discover our top product AMACR Primary Antibody
  • Application Notes
    Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: 1/25-1/50 in anABC method (30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Prostate carcinoma.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
    Alternative Name
    AMACR / RACE (AMACR Products)
    Background
    P504S (AMARC) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.Synonyms: 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, P504S
    Gene ID
    23600
    NCBI Accession
    NP_055139
    UniProt
    Q9UHK6
    Pathways
    Monocarboxylic Acid Catabolic Process
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