Podoplanin antibody

Catalog No. ABIN115687

Product Details anti-Podoplanin Antibody

Target: Podoplanin (PDPN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Specificity: Podoplanin

Purification: Protein A affinity chromatography

Immunogen: Recombinant ectodomain of Podoplanin (gp36)

Application Details

Application Notes: Immunoprecipitation (2-4 g/sample). Immunofluorescence (1-2 g). Western blotting (1-2 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled sterile water to >0.5 mg/mL.

Buffer: PBS, pH 7.4, containing no preservative

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: The lyophilized IgG is stable at 2-8 °C for one month and for one year from despatch when kept at -20 °C. When reconstituted in sterile water, the antibody is stable for six weeks at 2-4 °C in the presence of a preservative. Reconstituted antibody can also be aliquotted and stored at -20 °C to -70 °C for 6 months without detectable loss of activity.

Expiry Date: 12 months

References for anti-Podoplanin antibody (ABIN115687)

Conrad, Niess, Huss, Huber, von Luettichau, Nelson, Ott, Jauch, Bruns: "Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo." in: Circulation, Vol. 119, Issue 2, pp. 281-9, (2009) (PubMed).

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin (PDPN Products)

Synonyms: PDPN antibody, AGGRUS antibody, GP36 antibody, GP40 antibody, Gp38 antibody, HT1A-1 antibody, OTS8 antibody, PA2.26 antibody, T1A antibody, T1A-2 antibody, OTS-8 antibody, RANDAM-2 antibody, T1-alpha antibody, T1a antibody, T1alpha antibody, E11 antibody, RTI40 antibody, podoplanin antibody, PDPN antibody, Pdpn antibody

Background: Podoplanin is a highly O-glycosylated integral membrane protein that is specifically expressed in the epithelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, Podoplanin colocalized with VEGFR-3/FLT-4, another marker for lymphatic endothelial cells.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha

Gene ID: 10630

NCBI Accession: NP_001006625

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport