CD48 antibody

Catalog No. ABIN118221

Product Details anti-CD48 Antibody

Target: CD48

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD48 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: This antibody recognises CD48, a ligand for CD2 cell surface antigen . MRC OX-78 labels thymocytes, B and T cells and macrophages.

Purification: Affinity chromatography on Protein G

Immunogen: Recombinant soluble mouse CD48. Spleen cells from immunised AO Rats were fused with cells from the Rat Y3 myeloma cell line.

Clone: OX-78

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD48

Target: CD48

Alternative Name: CD48 (CD48 Products)

Background: CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.Synonyms: B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, Leukocyte antigen MEM-102, MEM-102, TCT.1

Gene ID: 12506

NCBI Accession: NP_031675

UniProt: P18181