CD40 Ligand antibody (Biotin)
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- Target See all CD40 Ligand (CD40LG) Antibodies
- CD40 Ligand (CD40LG)
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Reactivity
- Mouse
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Host
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Hamster
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Clonality
- Monoclonal
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Conjugate
- This CD40 Ligand antibody is conjugated to Biotin
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Application
- Flow Cytometry (FACS)
- Specificity
- Mouse CD154, Mr 39 kDa
- Characteristics
- Hamster Anti-Mouse CD154-BIOT
- Immunogen
- Activated mouse Th1 clone D1.6
- Clone
- MR1
- Isotype
- IgG
- Top Product
- Discover our top product CD40LG Primary Antibody
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- Application Notes
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , ELISA - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Comment
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In vivo and in vitro blockage of CD154 function
- Sample Volume
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg in 1.0 mL of PBS/Sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Storage
- 4 °C
- Storage Comment
- Store at 2-8°C
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- Target
- CD40 Ligand (CD40LG)
- Alternative Name
- CD154 (CD40LG Products)
- Background
- CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporin-sensitive.
- Pathways
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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