CD40 Ligand antibody (AA 33-62)
Quick Overview for CD40 Ligand antibody (AA 33-62) (ABIN3028551)
Target
See all CD40 Ligand (CD40LG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 33-62
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Purpose
- TRAP Antibody / CD40L
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Cross-Reactivity (Details)
- Expected species reactivity: Bovine, Pig
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Purification
- Purified
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Immunogen
- A portion of amino acids 33-62 from the human protein was used as the immunogen for this TRAP antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the TRAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the TRAP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD40 Ligand (CD40LG)
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Alternative Name
- TRAP
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Background
- TRAP/CD154/CD40L is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in its gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
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UniProt
- P29965
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Pathways
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
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