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CD93 Molecule (CD93) antibody

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Synonyms 6030404G09Rik, AA145088, AA4.1, AW555904, C1qr1, C1qrp, Ly68, C1QR1, C1qR(P), C1qRP, CDw93, ECSM3, MXRA4, dJ737E23.1, C1qRp
(65), (51), (31), (10)
(35), (32), (22)
Clonality (Clone)
Monoclonal ()
(9), (8), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
(39), (27), (22), (19), (12), (11), (6), (5), (5), (4), (4), (3), (2), (2), (2), (1)
Pubmed 4 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen LPS-stimulated U937
Clone MNI-11
Isotype IgG1
Specificity This antibody reacts with CD93 antigen. mNI-11 has been reported to induce intercellular adhesion of LPS-stimulated monocyte (U937) cells as well as inducing the adhesion of these cells to an endothelial (HUVEC) cell layer and rapid spread formation in HUVECs.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A agarose
Alternative Name CD93 / C1QR1 (CD93 Antibody Abstract)
Background CD93, also known as C1qRp, is a 100-125 kDa type I membrane protein that is a receptor for the complement protein C1q. CD93 has also been shown to act as a receptor for mannose-binding lectin and surfactant protein A. CD93 is expressed on the surface of monocytes, granulocytes, and endothelial cells, and expression is increased by TNF-α or GM-CSF. CD93 is involved in ligand-mediated enhancement of phagocytosis and intercellular adhesion.Synonyms: C1q receptor, C1q/MBL/SPA receptor, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, MBL receptor, MXRA4, Matrix-remodeling-associated protein 4, SPA receptor
Gene ID 22918
NCBI Accession NP_036204
UniProt Q9NPY3
Research Area CD Antigens
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Upon receipt, store (in aliqouts) at -20 °C.
Supplier Images
Immunohistochemistry (IHC) image for anti-CD93 Molecule (CD93) antibody (ABIN1449221) anti-CD93 Molecule (CD93) antibody
Flow Cytometry (FACS) image for anti-CD93 Molecule (CD93) antibody (ABIN1449221) anti-CD93 Molecule (CD93) antibody (Image 2)
Flow Cytometry (FACS) image for anti-CD93 Molecule (CD93) antibody (ABIN1449221) anti-CD93 Molecule (CD93) antibody (Image 3)
Western Blotting (WB) image for anti-CD93 Molecule (CD93) antibody (ABIN1449221) anti-CD93 Molecule (CD93) antibody (Image 4)
Background publications Ikewaki, Tamauchi, Inoko: "Decrease in CD93 (C1qRp) expression in a human monocyte-like cell line (U937) treated with various apoptosis-inducing chemical substances." in: Microbiology and immunology, Vol. 51, Issue 12, pp. 1189-200, 2007 (PubMed).

Ikewaki, Kulski, Inoko: "Regulation of CD93 cell surface expression by protein kinase C isoenzymes." in: Microbiology and immunology, Vol. 50, Issue 2, pp. 93-103, 2006 (PubMed).

McGreal, Ikewaki, Akatsu et al.: "Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 10, pp. 5222-32, 2002 (PubMed).

Ikewaki, Inoko: "Development and characterization of a novel monoclonal antibody (mNI-11) that induces cell adhesion of the LPS-stimulated human monocyte-like cell line U937." in: Journal of leukocyte biology, Vol. 59, Issue 5, pp. 697-708, 1996 (PubMed).

Catalog No. ABIN1449221
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