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CD93 Molecule (CD93) antibody

Details for Product No. ABIN1449221
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Antigen
Synonyms C1QR1, C1qRP, CDw93, ECSM3, MXRA4, C1qR(P), dJ737E23.1, 6030404G09Rik, AA145088, AA4.1, AW555904, C1qr1, C1qrp, Ly68, C1qRp
Reactivity
Human
(59), (52), (30), (17), (12), (12)
Host
Mouse
(30), (29), (22)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(11), (6), (6), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
(56), (24), (18), (18), (10), (9), (8), (7), (2), (1), (1)
Pubmed 4 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN1449221
308.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen LPS-stimulated U937
Clone MNI-11
Isotype IgG1
Specificity This antibody reacts with CD93 antigen. mNI-11 has been reported to induce intercellular adhesion of LPS-stimulated monocyte (U937) cells as well as inducing the adhesion of these cells to an endothelial (HUVEC) cell layer and rapid spread formation in HUVECs.
Purification Protein A agarose
Alternative Name CD93 / C1QR1
Background CD93, also known as C1qRp, is a 100-125 kDa type I membrane protein that is a receptor for the complement protein C1q. CD93 has also been shown to act as a receptor for mannose- binding lectin and surfactant protein A. CD93 is expressed on the surface of monocytes, granulocytes, and endothelial cells, and expression is increased by TNF-alpha or GM-CSF. CD93 is involved in ligand-mediated enhancement of phagocytosis and intercellular adhesion.
Alternate names: C1q receptor, C1q/MBL/SPA receptor, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, MBL receptor, MXRA4, Matrix-remodeling- associated protein 4, SPA receptor
Gene ID 22918
NCBI Accession NP_036204.2
UniProt Q9NPY3
Research Area CD Antigens
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Upon receipt, store (in aliqouts) at -20 °C.
Expiry Date 12 months
Supplier Images
anti-CD93 Molecule (CD93) antibody anti-CD93 Molecule (CD93) antibody
anti-CD93 Molecule (CD93) antibody (2) anti-CD93 Molecule (CD93) antibody (Image 2)
anti-CD93 Molecule (CD93) antibody (3) anti-CD93 Molecule (CD93) antibody (Image 3)
anti-CD93 Molecule (CD93) antibody (4) anti-CD93 Molecule (CD93) antibody (Image 4)
Background publications Ikewaki, Inoko: "Development and characterization of a novel monoclonal antibody (mNI-11) that induces cell adhesion of the LPS-stimulated human monocyte-like cell line U937." in: Journal of leukocyte biology, Vol. 59, Issue 5, pp. 697-708, 1996 (PubMed).

McGreal, Ikewaki, Akatsu et al.: "Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 10, pp. 5222-32, 2002 (PubMed).

Ikewaki, Kulski, Inoko: "Regulation of CD93 cell surface expression by protein kinase C isoenzymes." in: Microbiology and immunology, Vol. 50, Issue 2, pp. 93-103, 2006 (PubMed).

Ikewaki, Tamauchi, Inoko: "Decrease in CD93 (C1qRp) expression in a human monocyte-like cell line (U937) treated with various apoptosis-inducing chemical substances." in: Microbiology and immunology, Vol. 51, Issue 12, pp. 1189-200, 2007 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1449221
308.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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