TFG antibody

Details for Product No. ABIN1449384
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Antigen
Synonyms wu:fb11c10, zgc:55342, zgc:77230, HMSNP, SPG57, TF6, TRKT3, AI173908
Reactivity
Human
(30), (4), (4), (2), (2), (1), (1), (1), (1), (1)
Host
Mouse
(24), (6)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(30), (15), (5), (4), (3), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN1449384
357.50 $
Plus shipping costs $45.00

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Human recombinant protein Trx-his-NTFG.
Clone TFG-03
Isotype IgG2b
Specificity This Monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa protein with regulatory functions.
Purification Affinity Chromatography on Protein A
Background TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.
Alternate names: TRK-fused gene protein
Gene ID 10342
NCBI Accession NP_001007566
UniProt Q92734
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Azide Free PBS, pH~7.4 preserved by filter sterilization
Preservative Azide free
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Matsuda, Suzuki, Honda et al.: "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways." in: Oncogene, Vol. 22, Issue 21, pp. 3307-18, 2003 (PubMed).

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