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TFG antibody
TFG
Reactivity: Human
WB, IP, IF
Host: Mouse
Monoclonal
TFG-03
unconjugated
Product Details anti-TFG Antibody
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Target
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TFG
(Trk-Fused Gene (TFG))
Reactivity
All reactivities for TFG antibodies
Human
Host
All hosts for TFG antibodies
Mouse
Clonality
All clonalities for TFG antibodies
Monoclonal
Conjugate
All conjugates for TFG antibodies
This TFG antibody is un-conjugated
Application
All applications for TFG antibodies
Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity Chromatography on Protein A
Immunogen
Human recombinant protein Trx-his-NTFG.
Clone
TFG-03
Isotype
IgG2b
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Azide Free PBS, pH ~7.4 preserved by filter sterilization
Preservative
Azide free
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for TFG
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Target
TFG
(Trk-Fused Gene (TFG))
Alternative Name
TFG (TFG Products )
Synonyms
wu:fb11c10 antibody, zgc:55342 antibody, zgc:77230 antibody, HMSNP antibody, SPG57 antibody, TF6 antibody, TRKT3 antibody, AI173908 antibody, trk-fused gene antibody, TRK-fused gene antibody, Trk-fused gene antibody, tfg antibody, TFG antibody, Tfg antibody
Background
TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.Synonyms: TRK-fused gene protein
Gene ID
10342
NCBI Accession
NP_001007566
UniProt
Q92734
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