TFG antibody

Catalog No. ABIN1449384

Product Details anti-TFG Antibody

Target: TFG (Trk-Fused Gene (TFG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TFG antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogen: Human recombinant protein Trx-his-NTFG.

Clone: TFG-03

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Azide Free PBS, pH ~7.4 preserved by filter sterilization

Preservative: Azide free

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TFG

Target: TFG (Trk-Fused Gene (TFG))

Alternative Name: TFG (TFG Products)

Background: TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.Synonyms: TRK-fused gene protein

Gene ID: 10342

NCBI Accession: NP_001007566

UniProt: Q92734