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Details for Product No. ABIN1449384

TFG antibody

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Antigen
Synonyms HMSNP, SPG57, TF6, TRKT3, AI173908, zgc:55342, zgc:77230, wu:fb11c10
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN1449384
Quantity 0.1 mg
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

Product details

Target Details Application Details Handling References Alternatives back to top
Immunogen Human recombinant protein Trx-his-NTFG.
Clone TFG-03
Isotype IgG2b
Specificity This Monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa protein with regulatory functions.
Purification Affinity Chromatography on Protein A

Target Details

Application Details Handling References Alternatives back to top
Background TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.
Alternate names: TRK-fused gene protein
Gene ID 10342
NCBI Accession NP_001007566.1
UniProt Q92734

Application Details

Target Details Handling References Alternatives back to top
Restrictions For Research Use only

Handling

Target Details Application Details References Alternatives back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer Azide Free PBS, pH~7.4 preserved by filter sterilization
Preservative Azide free
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months

References

Target Details Application Details Handling Alternatives back to top
Background publications Matsuda, Suzuki, Honda et al.: "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways." in: Oncogene, Vol. 22, Issue 21, pp. 3307-18, 2003 (PubMed).

Alternatives

Target Details Application Details Handling References back to top
Alternatives for antigen "TFG", type "Antibodies"
Hosts (12), (6)
Reactivities (18), (4), (3), (3), (3), (3), (2), (2), (1), (1)
Applications (18), (6), (4), (3), (3), (1), (1), (1)
Epitopes (4), (2), (1), (1), (1), (1)
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