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TFG antibody

TFG Reactivity: Human WB, IP, ICC Host: Mouse Monoclonal TFG-03 unconjugated
Catalog No. ABIN1558081
  • Target See all TFG Antibodies
    TFG (Trk-Fused Gene (TFG))
    Reactivity
    • 51
    • 14
    • 9
    Human
    Host
    • 45
    • 6
    Mouse
    Clonality
    • 38
    • 13
    Monoclonal
    Conjugate
    • 24
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFG antibody is un-conjugated
    Application
    • 43
    • 27
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificity
    The mouse monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa intracellular protein with regulatory functions.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Human recombinant protein Trx-his-NTFG
    Clone
    TFG-03
    Isotype
    IgG2b
    Top Product
    Discover our top product TFG Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    TFG (Trk-Fused Gene (TFG))
    Alternative Name
    TFG (TFG Products)
    Synonyms
    wu:fb11c10 antibody, zgc:55342 antibody, zgc:77230 antibody, HMSNP antibody, SPG57 antibody, TF6 antibody, TRKT3 antibody, AI173908 antibody, trk-fused gene antibody, TRK-fused gene antibody, Trk-fused gene antibody, tfg antibody, TFG antibody, Tfg antibody
    Background
    Trafficking from ER to golgi regulator,TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.,TF6, TRKT3, SPG57
    Gene ID
    10342
    UniProt
    Q92734
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