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SMAD7 antibody (SMAD, Mothers Against DPP Homolog 7) (N-Term)

Details for Product anti-SMAD7 Antibody No. ABIN182475, Supplier: Login to see New
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Synonyms CRCS3, MADH7, MADH8, Madh7, Smad10, madh7, xsmad7, Smad7a
(11), (10), (7), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2)
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(78), (21), (20), (3), (2), (1), (1), (1)
(58), (22)
Western Blotting (WB)
(77), (29), (16), (14), (11), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human SMAD7
Blocking Peptide Blocking peptide for this product available: ABIN984106
Predicted Reactivity Human : 100 %, Bovine : 90 %, Dog : 90 %, Mouse : 90 %, Pig : 90 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against SMAD7. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SMAD7 (SMAD7 Antibody Abstract)
Background Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
Molecular Weight 46 kDa
Gene ID 4092
NCBI Accession NP_005895, NM_005904
UniProt O15105
Research Area Signaling, Transcription Factors
Pathways Interferon-gamma Pathway
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 426 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-SMAD7 antibody (SMAD, Mothers Against DPP Homolog 7) (N-Term) (ABIN182475) anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (N-Term) antibody
Western Blotting (WB) image for anti-SMAD7 antibody (SMAD, Mothers Against DPP Homolog 7) (N-Term) (ABIN182475) WB Suggested Anti-SMAD7 Antibody
Positive Control: Lane 1:41 µg Flag-SMAD7 tra...
Background publications Komuro, Imamura, Saitoh et al.: "Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)." in: Oncogene, Vol. 23, Issue 41, pp. 6914-23, 2004 (PubMed).

Catalog No. ABIN182475
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