Cyclin L1 (CCNL1) (N-Term) antibody

Details for Product No. ABIN182754
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Antigen
Synonyms MGC132032, bm-001, ania-6a, pro1073, MGC108436, Ccnl1, ANIA6A, PRO1073, MCM2, 2610030E23Rik, AU018493, Ccnl, Ania-6a, cyclin-L1, ccnl1, fd99b09, wu:fd99b09, zgc:55544
Epitope
N-Term
(4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(44), (29), (27), (13), (11), (11), (2), (1)
Host
Rabbit
(42), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(34), (20), (14), (11), (10), (9), (8), (2), (1)
Pubmed 2 references available
Quantity 100 µg
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Catalog No. ABIN182754
229.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human CCNL1
Sequence TTTTTTGGIL IGDRLYSEVS LTIDHSLIPE ERLSPTPSMQ DGLDLPSETD
Predicted Reactivity Bovine : 100 %, Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Rabbit : 90 %
Characteristics This is a rabbit polyclonal antibody against CCNL1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name CCNL1
Background CCNL1 plays a critical role in the loco-regional progression of HNSCC and may serve as an indicator for occult advanced tumour stages. CCNL1 also plays a role in pre-mRNA splicing, has been shown to associate with the PITSLRE kinase, and is involved in pre-mRNA processing.
Molecular Weight 60 kDa
Gene ID 57018
NCBI Accession NP_064703, NM_020307
UniProt Q8NI48
Research Area Chromatin and Nuclear Signaling, DNA/RNA, Cell Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 526 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Cyclin L1 (CCNL1) (N-Term) antibody WB Suggested Anti-CCNL1 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

General Clark, Edwards, Peterson et al.: "Fugu ESTs: new resources for transcription analysis and genome annotation." in: Genome research, Vol. 13, Issue 12, pp. 2747-53, 2003 (PubMed).

Validation Images
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