Cyclin L1 antibody (C-Term)

Catalog No. ABIN6261157

The Rabbit Polyclonal anti-Cyclin L1 antibody (ABIN6261157) specifically detects Cyclin L1 in WB, IHC, IF and ICC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Cyclin L1 antibody (C-Term) (ABIN6261157)

Target: Cyclin L1 (CCNL1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Cyclin L1 Antibody

Binding Specificity: C-Term

Purpose: Cyclin L1 Antibody

Specificity: Cyclin L1 Antibody detects endogenous levels of total Cyclin L1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cyclin L1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Cyclin L1

Target: Cyclin L1 (CCNL1)

Alternative Name: Cyclin L1

Background:

Description: Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) (PubMed:18216018). Inhibited by the CDK-specific inhibitor CDKN1A/p21 (PubMed:11980906). May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) (PubMed:12414649, PubMed:15700036).

Gene: CCNL1

Molecular Weight: 60kDa

Gene ID: 57018

UniProt: Q9UK58