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SATB Homeobox 1 (SATB1) (C-Term) antibody

Details for Product No. ABIN182789
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Antigen
Synonyms SATB1, 2610306G12Rik, AW413156
Epitope
C-Term
(15), (12), (10), (7), (5), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human, Chicken
(70), (38), (25), (13), (13), (13), (12)
Host
Rabbit
(50), (16), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(59), (27), (22), (18), (10), (10), (4), (4), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 50 µg
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Catalog No. ABIN182789
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human SATB1
Sequence PPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPRTK ISVEALGILQ
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Rabbit : 100 %, Mouse : 90 %, Rat : 90 %, Chicken : 80 %
Characteristics This is a rabbit polyclonal antibody against SATB1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SATB1
Background SATB1 binds to DNA at special AT-rich sequences at nuclear matrix- or scaffold-associated regions. SATB1 was thought to recognize the sugar-phosphate structure of double-stranded DNA.
Molecular Weight 86 kDa
Gene ID 6304
NCBI Accession NM_002971, NP_002962
UniProt Q01826
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 763 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Product cited in: Green, Roeder: "Definition of a novel promoter for the major adenovirus-associated virus mRNA." in: Cell, Vol. 22, Issue 1 Pt 1, pp. 231-42, 1981 (PubMed).

Background publications Pavan Kumar, Purbey, Sinha et al.: "Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo." in: Molecular cell, Vol. 22, Issue 2, pp. 231-43, 2006 (PubMed).

Validation Images
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