2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) (N-Term) antibody

Details for Product No. ABIN182899
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Antigen
Synonyms cnpl, fd21d08, fi37a10, rich, sb:cb662, si:ch73-158e11.4, wu:fd21d08, wu:fd44a05, wu:fi35d08, wu:fi37a10, CNP, DKFZp469F1421, CNPase, Cnp-1, Cnp1, CNP1, CNPF, CNPI, CNPII, lbab
Epitope
N-Term
(5), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity
Rat (Rattus), Cow (Bovine), Human
(79), (37), (32), (12), (12), (7), (3)
Host
Rabbit
(56), (18), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunoprecipitation (IP), Western Blotting (WB)
(66), (24), (22), (18), (15), (11), (10), (5), (4), (3), (3), (2), (2), (1), (1), (1)
Pubmed 2 references available
Quantity 100 µg
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Catalog No. ABIN182899
229.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human CNP
Sequence YKITPGARGA FSEEYKRLDE DLAAYCRRRD IRILVLDDTN HERERLEQLF
Predicted Reactivity Horse : 100 %, Dog : 90 %, Pig : 90 %
Characteristics This is a rabbit polyclonal antibody against CNP. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name CNP
Background 2',3'-Cyclic nucleotide-3'-phosphodiesterase (CNP1 and CNP2) is the major enzyme of central nervous system myelin. It is associated with oligodendroglial plasma membrane and uncompacted myelin (myelin-like fraction), which are in contact with glial cytoplasm
Molecular Weight 45 kDa
Gene ID 1267
NCBI Accession NP_149124, NM_033133
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 401 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) (N-Term) antibody WB Suggested Anti-CNP Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysate
anti-2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) (N-Term) antibody (2) Lanes: 1. Human NT-2 cells (641 µg) lysate 2. Rat brain extract (841 µg)
Primary Antibody Dilution: 2 µg/mL
Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience
Secondary Antibody Dilution: 1: 0,000
Gene Name: CNP

Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science
Background publications Peirce, Bray, Williams et al.: "Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia." in: Archives of general psychiatry, Vol. 63, Issue 1, pp. 18-24, 2006 (PubMed).

General Peirce, Petry, Stitzer et al.: "Effects of lower-cost incentives on stimulant abstinence in methadone maintenance treatment: a National Drug Abuse Treatment Clinical Trials Network study." in: Archives of general psychiatry, Vol. 63, Issue 2, pp. 201-8, 2006 (PubMed).

Validation Images
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