Cnpase antibody (N-Term)

Catalog No. ABIN2778175

This Rabbit Polyclonal antibody specifically detects Cnpase in WB and IP. It exhibits reactivity toward Human, Rat, Sheep, Dog, Pig, Horse and Cow.

Quick Overview for Cnpase antibody (N-Term) (ABIN2778175)

Target: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Reactivity: Human, Rat, Sheep, Dog, Pig, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cnpase antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Cnpase Antibody

Binding Specificity: N-Term

Purpose: CNP Antibody - N-terminal region

Sequence: YKITPGARGA FSEEYKRLDE DLAAYCRRRD IRILVLDDTN HERERLEQLF

Predicted Reactivity: Cow: 85%, Dog: 92%, Horse: 100%, Human: 100%, Pig: 92%, Rat: 77%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against CNP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093603

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cnpase

Target: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Alternative Name: CNP

Background:

Background Information: 2',3'-Cyclic nucleotide-3'-phosphodiesterase (CNP1 and CNP2) is the major enzyme of central nervous system myelin. It is associated with oligodendroglial plasma membrane and uncompacted myelin (myelin-like fraction), which are in contact with glial cytoplasm

Gene Name: 2',3'-cyclic nucleotide 3' phosphodiesterase

Alternative Symbols: CNP1, HLD20

Protein Name: 2',3'-cyclic-nucleotide 3'-phosphodiesterase

Molecular Weight: 45kDa

Gene ID: 1267

NCBI Accession: NP_149124

UniProt: P09543