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Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody

Details for Product No. ABIN182912, Supplier: Login to see New
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Synonyms A630044F12Rik, AI465270, AW229127, Cbfa2t3h, ETO-2, Eto2, MTGR2, MTG16a, MTG16b, ETO2, MTG16, ZMYND4
(5), (3), (2), (1), (1), (1)
Chicken, Human, Mouse (Murine), Rat (Rattus)
(24), (10), (6), (1)
(20), (4)
Western Blotting (WB)
(18), (12), (6), (5), (1)
Pubmed 1 reference available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human CBFA2T3
Blocking Peptide Blocking peptide for this product available: ABIN974494
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Bovine : 90 %, Dog : 90 %, Chicken : 80 %, Horse : 80 %
Characteristics This is a rabbit polyclonal antibody against CBFA2T3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CBFA2T3 (CBFA2T3 Antibody Abstract)
Background The t(16,21)(q24,q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Molecular Weight 62 kDa
Gene ID 863
NCBI Accession NP_787127, NM_175931
UniProt O75082
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 567 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody (ABIN182912) WB Suggested Anti-CBFA2T3 Antibody Titration: 0.2-1 ug/ml
Positive Contr...
Background publications Powell, Gardner, Bais et al.: "Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes." in: Genomics, Vol. 80, Issue 3, pp. 303-10, 2002 (PubMed).

Catalog No. ABIN182912
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