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Details for Product No. ABIN182912

Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody

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Antigen
Synonyms A630044F12Rik, AI465270, AW229127, Cbfa2t3h, ETO-2, Eto2, MTGR2, MTG16a, MTG16b, ETO2, MTG16, ZMYND4
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Human, Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN182912
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-CBFA2T3 antibody: synthetic peptide directed towards the N terminal of human CBFA2T3
Sequence QPRSTPPSMPPPPPAASQGATRPPSFTPHTLMNGSSHSPT AINGAPCTPN
Predicted Reactivity Guinea pig : 100%, Human : 100%, Mouse : 100%, Rat : 100%, Bovine : 92%, Dog : 92%, Chicken : 84%, Horse : 84%
Characteristics This is a rabbit polyclonal antibody against CBFA2T3. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name CBFA2T3
Background The t(16,21)(q24,q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Molecular Weight 62kDa
Gene ID 863
NCBI Accession NP_787127, NM_175931
UniProt O75082
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-CBFA2T3 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Powell, Gardner, Bais et al.: "Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes." in: Genomics, Vol. 80, Issue 3, pp. 303-10, 2002 (PubMed).

Alternatives for antigen "Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3)", type "Antibodies"
Hosts (11), (2)
Reactivities (13), (7), (3), (1)
Applications (8), (7), (4), (3), (2)
Epitopes (4), (2), (1)
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