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Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody

Details for Product No. ABIN182912
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Antigen
Synonyms A630044F12Rik, AI465270, AW229127, Cbfa2t3h, ETO-2, Eto2, MTGR2, MTG16a, MTG16b, ETO2, MTG16, ZMYND4
Epitope
N-Term
(4), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human, Chicken
(14), (7), (3), (1)
Host
Rabbit
(12), (2)
Clonality
Polyclonal
Application
Western Blotting (WB)
(9), (7), (4), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
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Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN182912
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the N terminal of human CBFA2T3
Sequence QPRSTPPSMPPPPPAASQGATRPPSFTPHTLMNGSSHSPT AINGAPCTPN
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Bovine : 90 %, Dog : 90 %, Chicken : 80 %, Horse : 80 %
Characteristics This is a rabbit polyclonal antibody against CBFA2T3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CBFA2T3
Background The t(16,21)(q24,q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Molecular Weight 62 kDa
Gene ID 863
NCBI Accession NM_175931, NP_787127
UniProt O75082
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 567 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody WB Suggested Anti-CBFA2T3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
Background publications Powell, Gardner, Bais et al.: "Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes." in: Genomics, Vol. 80, Issue 3, pp. 303-10, 2002 (PubMed).

Hosts (12), (2)
Reactivities (14), (7), (3), (1)
Applications (9), (7), (4), (3), (2), (1)
Epitopes (4), (2), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN182912
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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