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Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (N-Term) antibody

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Antigen
Epitope
N-Term
(14), (6), (6), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(37), (10), (8), (3), (2), (2), (2), (1)
Host
Rabbit
(24), (13)
Clonality
Polyclonal
Application
Western Blotting (WB)
(35), (21), (12), (9), (9), (8), (3), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human TIP120A
Sequence TVIGELPPAS SGSALAANVC KKITGRLTSA IAKQEDVSVQ LEALDIMADM
Predicted Reactivity Bovine :100 %,   African clawed frog :100 %,   Western clawed frog :100 %,   Zebrafish :100 %,   Sumatran orangutan :100 %,   Green puffer :100 %,   Rat :100 %,   Mouse :100 %,   Human :100 %,   Florida lancelet :90 %,   Starlet sea anemone :90 %,   Dog :80 %,   Body louse :70 %,  
Characteristics This is a rabbit polyclonal antibody against TIP120A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name TIP120A (CAND1 Antibody Abstract)
Background TIP120A functions as a negative regulator of SCF E3 ubiquitin ligases and may modulate other cullin ligases in a similar fashion.
Molecular Weight 136 kDa
Gene ID 55832
NCBI Accession NP_060918, NM_018448
UniProt Q86VP6
Research Area Chromatin and Nuclear Signaling, Cell Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1230 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (N-Term) antibody (ABIN183042) anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (N-Term) antibody
Background publications Min, Hwang, Lee et al.: "TIP120A associates with cullins and modulates ubiquitin ligase activity." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 15905-10, 2003 (PubMed).

Catalog No. ABIN183042

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