TRIP13 antibody (C-Term)

Catalog No. ABIN183656

Product Details anti-TRIP13 Antibody

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LSGRVLRKLP FLAHALYVQA PTVTIEGFLQ ALSLAVDKQF EERKKLAAYI

Predicted Reactivity: Cow: 91%, Dog: 100%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TRIP13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TRIP13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 432 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIP13

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Alternative Name: TRIP13 (TRIP13 Products)

Synonyms: im:6901078 antibody, zgc:65952 antibody, 16e1bp antibody, pch2 antibody, trip-13 antibody, TRIP13 antibody, 16E1BP antibody, PCH2 antibody, TRIP-13 antibody, 2410002G23Rik antibody, D13Ertd328e antibody, thyroid hormone receptor interactor 13 antibody, pachytene checkpoint protein 2 homolog antibody, pachytene checkpoint protein 2 homolog pseudogene antibody, thyroid hormone receptor interactor 13 L homeolog antibody, trip13 antibody, TRIP13 antibody, LOC742208 antibody, CMU_027690 antibody, MCYG_05496 antibody, LOC100348391 antibody, trip13.L antibody, Trip13 antibody

Background: The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.
Alias Symbols: 16E1BP
Protein Interaction Partner: KRTAP26-1, KRTAP12-1, KRTAP12-2, MORN3, TEX37, METTL15, MGAT5B, C4orf33, GLYCTK, M1AP, LRR1, LNX1, RHOXF2, LOXL4, ZNF34, FNDC3B, TINAGL1, PBLD, SEMA4G, SPRYD7, PELI1, PLSCR3, PCMTD2, CYB5R2, AMDHD2, TNRC6A, DIP2A, DPYSL4, TRIP13, SIGLEC5, TPT1, SCP2, QARS
Protein Size: 432

Molecular Weight: 49 kDa

Gene ID: 9319

NCBI Accession: NM_004237, NP_004228

UniProt: Q15645