TRIP13 antibody (AA 181-390)

Catalog No. ABIN7162475

Product Details anti-TRIP13 Antibody

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Binding Specificity: AA 181-390

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Pachytene checkpoint protein 2 homolog protein (181-390AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRIP13

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Alternative Name: TRIP13 (TRIP13 Products)

Synonyms: im:6901078 antibody, zgc:65952 antibody, 16e1bp antibody, pch2 antibody, trip-13 antibody, TRIP13 antibody, 16E1BP antibody, PCH2 antibody, TRIP-13 antibody, 2410002G23Rik antibody, D13Ertd328e antibody, thyroid hormone receptor interactor 13 antibody, pachytene checkpoint protein 2 homolog antibody, pachytene checkpoint protein 2 homolog pseudogene antibody, thyroid hormone receptor interactor 13 L homeolog antibody, trip13 antibody, TRIP13 antibody, LOC742208 antibody, CMU_027690 antibody, MCYG_05496 antibody, LOC100348391 antibody, trip13.L antibody, Trip13 antibody

Background:

Background: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959).

Aliases: 16E1-BP antibody, 16E1BP antibody, Homo sapiens HPV16 E1 protein binding protein mRNA complete cds antibody, HPV16 E1 protein binding protein antibody, HPV16 E1 protein-binding protein antibody, Human papillomavirus type 16 E1 protein binding protein antibody, Human papillomavirus type 16 E1 protein-binding protein antibody, Pachytene checkpoint protein 2 homolog antibody, PCH2 antibody, Thyroid hormone receptor interactor 13 antibody, Thyroid receptor interacting protein 13 antibody, Thyroid receptor-interacting protein 13 antibody, TR-interacting protein 13 antibody, TRIP-13 antibody, Trip13 antibody, TRP13_HUMAN antibody

UniProt: Q15645