Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (Middle Region) antibody

Details for Product No. ABIN183963
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Antigen
Synonyms PRKRA, AV120107, PRK, Pact, RAX, lear, DYT16, PACT, im:7151758, zgc:162619, dyt16, pact, prkra-a, prkra-b, rax, rbpa
Epitope
Middle Region
(9), (5), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human
(56), (6), (6), (2), (1)
Host
Rabbit
(45), (12)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(42), (26), (14), (11), (9), (7), (4), (3), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN183963
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human PRKRA
Sequence RLPEYTLSQE GGPAHKREYT TICRLESFME TGKGASKKQA KRNAAEKFLA
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against PRKRA. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name PRKRA
Background PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA).
Molecular Weight 34 kDa
Gene ID 8575
NCBI Accession NP_003681, NM_003690
UniProt O75569
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 313 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (Middle Region) antibody WB Suggested Anti-PRKRA Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (Middle Region) antibody (2) anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (Middle Region) antibody (Image 2)
Background publications Lee, Hur, Park et al.: "The role of PACT in the RNA silencing pathway." in: The EMBO journal, Vol. 25, Issue 3, pp. 522-32, 2006 (PubMed).

Validation Images
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