Exosome Component 3 (EXOSC3) (C-Term) antibody

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Antigen
Epitope
C-Term
(7), (7), (4), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(40), (11), (11), (5), (3), (2), (1)
Host
Rabbit
(28), (12)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(37), (13), (10), (6), (5), (4), (2), (2), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the C terminal of human EXOSC3
Sequence PLEIVFGMNG RIWVKAKTIQ QTLILANILE ACEHMTSDQR KQIFSRLAES
Predicted Reactivity Dog : 100 %, Horse : 100 %, Pig : 100 %, Guinea pig : 80 %, Mouse : 80 %
Characteristics This is a rabbit polyclonal antibody against EXOSC3. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name EXOSC3 (EXOSC3 Antibody Abstract)
Background EXOSC3 is component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA.
Molecular Weight 30 kDa
Gene ID 51010
NCBI Accession NM_016042, NP_057126
UniProt Q9NQT5
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 275 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Exosome Component 3 (EXOSC3) (C-Term) antibody (ABIN184036) WB Suggested Anti-EXOSC3 Antibody Titration: 2.5ug/ml
ELISA Titer: 1...
Immunohistochemistry (IHC) image for anti-Exosome Component 3 (EXOSC3) (C-Term) antibody (ABIN184036) anti-Exosome Component 3 (EXOSC3) (C-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Exosome Component 3 (EXOSC3) (C-Term) antibody (ABIN184036) WB Suggested Anti-EXOSC3
Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.12500 <...
Background publications Lehner, Sanderson: "A protein interaction framework for human mRNA degradation." in: Genome research, Vol. 14, Issue 7, pp. 1315-23, 2004 (PubMed).