SARS-CoV-2 Protein Interactome

SARS-CoV-2 is an enveloped, positive-sense, single-stranded RNA beta coronavirus belonging to the order of nidovirales. In the first three months since its initial identification in December 2019 SARS-CoV-2 has caused more than 800.000 confirmed cases and over 40.000 fatalities worldwide of the associated severe acute respiratory syndrome COVID-19 (coronavirus disease 2019)1.

Presently, no vaccine is available to curb the virus’ spread. A potential source for COVID-19 therapeutics are existing antiviral reagents that are either already approved or in development for the treatment of the other two respiratory syndromes – SARS and MERS – caused by human coronaviruses (hCoVs)2,3. A deeper understanding of the function of the virus and its proteins is essential for the targeted application of existing drugs and the discovery of new ones4,5,6.

The 30kb SARS-CoV-2 genome encodes 16 non-structural proteins (Nsp1-16), four structural proteins (spike, envelope, nucleocapsid, membrane), and nine putative accessory factors7. Many of these proteins and polypeptides have a number or interaction partners in particular in lung cells, the virus’ primary infection site. These interactions with the host cell determine the virus’ ability to infect the cell, reproduce its genome and trigger the production and release of new virus particles. In addition, several virus proteins appear to have interaction partners affecting innate immune pathways such as the interferon signaling pathway, NF-kappa B inflammatory response, type I interferon production, and IRF-3 activation.

At least some of the members of the third group of SARS-CoV-2 proteins, the nine accessory factors (Orf3a-10), have been implicated in driving progression of COVID-19. Orf3a induces apoptosis and is thought to activate NF-kB and the NLRP3 inflammasome involved in pyroptosis, a highly inflammatory form of apoptosis. The type I interferon (IFN) antagonists Orf6 and Orf9b inhibit the IFN response, the most important innate antiviral cytokines.

Some of these regulatory functions are shared with other pathogenic human viruses. Therefore, a deeper understanding of these mechanisms may lead to the identification of targets and development of novel therapeutics relevant for future virus pandemics.

SARS-CoV-2 Structural Proteins: SARS-CoV-2 Spike Protein, SARS-CoV-2 Nucleocapsid Protein, SARS-CoV-2 S1 (RBD) Protein, SARS-CoV-2 Spike Subunit S1 Protein, SARS-CoV-2 Subunit S2 Protein

SARS-CoV-2 Non-Structural Proteins: SARS-CoV-2 Non-Structural Proteins

SARS-CoV-2 Antibodies: anti-SARS-CoV-2 Antibodies

SARS-CoV Viral Proteins: , , , ,

Additional information and products: CoV-2 Resource, SARS-CoV-2 RT-PCR and qPCR Kits, SARS-CoV-2 ELISA Kits, SARS-CoV-2 Life Cycle Stages & Inhibition Targets

References:

  1. Dong, Ensheng; Du, Hongru; Gardner, L. An interactive web-based dashboard to track COVID-19 in real time. Lancet Infect. Dis. (2020).
  2. Morse, J. S., Lalonde, T., Xu, S. & Liu, W. R. Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019-nCoV. Chembiochem 21, 730–738 (2020).
  3. Li, G. & De Clercq, E. Therapeutic options for the 2019 novel coronavirus (2019-nCoV). Nat. Rev. Drug Discov. 19, 149–150 (2020).
  4. Báez-Santos, Y. M., St. John, S. E. & Mesecar, A. D. The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds. Antiviral Res. 115, 21–38 (2015).
  5. Kirchdoerfer, R. N. & Ward, A. B. Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors. Nat. Commun. 10, 2342 (2019).
  6. Coutard, B. et al. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade. Antiviral Res. 176, 104742 (2020).
  7. David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Matthew J. O’Meara, Jeffrey Z. Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Huettenhain, Robyn M. Kaake, Alicia L. Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, N. J. K. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug Repurposing. Nature. (2020).

CoV-2 Spike Protein

Antigens in this category:
ZDHHC5 (Zinc Finger, DHHC-Type Containing 5): ZDHHC5 antibodies    
GOLGA7 - Golgin A7: GOLGA7 antibodies   GOLGA7 Proteins

CoV-2 Nucleocapsid Protein

Antigens in this category:
CKIIALPHA - Casein Kinase II alpha Subunit: CKIIALPHA antibodies CKIIALPHA ELISA Kits  
RRP9 - Ribosomal RNA Processing 9, Small Subunit (SSU) Processome Component, Homolog (Yeast): RRP9 antibodies   RRP9 Proteins
UPF1 - UPF1 Regulator of Nonsense Transcripts Homolog (Yeast): UPF1 antibodies   UPF1 Proteins
MOV10 (Mov10, Moloney Leukemia Virus 10, Homolog (Mouse)): MOV10 antibodies   MOV10 Proteins
G3BP2 (GTPase Activating Protein (SH3 Domain) Binding Protein 2): G3BP2 antibodies   G3BP2 Proteins
PABPC4 - Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form): PABPC4 antibodies    
G3BP1 - GTPase Activating Protein (SH3 Domain) Binding Protein 1: G3BP1 antibodies G3BP1 ELISA Kits G3BP1 Proteins
LARP1 (La Ribonucleoprotein Domain Family, Member 1): LARP1 antibodies   LARP1 Proteins
FAM98A (Family with Sequence Similarity 98, Member A): FAM98A antibodies   FAM98A Proteins
PABPC1 - Poly(A) Binding Protein, Cytoplasmic 1: PABPC1 antibodies   PABPC1 Proteins
DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21): DDX21 antibodies   DDX21 Proteins
CSNK2B - Casein Kinase 2, beta: CSNK2B antibodies CSNK2B ELISA Kits CSNK2B Proteins
RPL36 - Ribosomal Protein L36: RPL36 antibodies   RPL36 Proteins
SNIP1 (Smad Nuclear Interacting Protein 1): SNIP1 antibodies SNIP1 ELISA Kits SNIP1 Proteins
RBM28 (RNA Binding Motif Protein 28): RBM28 antibodies   RBM28 Proteins
CSNK2A2 - Casein Kinase 2, alpha Prime Polypeptide: CSNK2A2 antibodies CSNK2A2 ELISA Kits CSNK2A2 Proteins

CoV-2 Envelope Protein

Antigens in this category:
ZC3H18 (Zinc Finger CCCH-Type Containing 18):      
Cwc27 (CWC27 Spliceosome-Associated Protein Homolog (S. Cerevisiae)): Cwc27 antibodies   Cwc27 Proteins
SLC44A2 (Solute Carrier Family 44, Member 2): SLC44A2 antibodies   SLC44A2 Proteins
AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit): AP3B1 antibodies   AP3B1 Proteins
BRD4 (Bromodomain Containing 4): BRD4 antibodies BRD4 ELISA Kits BRD4 Proteins
BRD2 (Bromodomain Containing 2): BRD2 antibodies   BRD2 Proteins

CoV-2 Membrane Protein

Antigens in this category:
ANO6 - Anoctamin 6: ANO6 antibodies ANO6 ELISA Kits ANO6 Proteins
AASS - Aminoadipate Semialdehyde Synthase: AASS antibodies   AASS Proteins
PSMD8 - Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8: PSMD8 antibodies   PSMD8 Proteins
PMPCB - Peptidase (Mitochondrial Processing) beta: PMPCB antibodies   PMPCB Proteins
GGCX (gamma-Glutamyl Carboxylase): GGCX antibodies   GGCX Proteins
REEP5 - Receptor Accessory Protein 5: REEP5 antibodies   REEP5 Proteins
INTS4 (Integrator Complex Subunit 4): INTS4 antibodies   INTS4 Proteins
ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide): ATP1B1 antibodies ATP1B1 ELISA Kits ATP1B1 Proteins
FAM8A1 - Family with Sequence Similarity 8, Member A1: FAM8A1 antibodies    
REEP6 (Receptor Accessory Protein 6): REEP6 antibodies   REEP6 Proteins
YIF1A - Yip1 Interacting Factor Homolog A (S. Cerevisiae): YIF1A antibodies   YIF1A Proteins
SAAL1 - serum Amyloid A-Like 1: SAAL1 antibodies SAAL1 ELISA Kits SAAL1 Proteins
TUBGCP2 (Tubulin, gamma Complex Associated Protein 2): TUBGCP2 antibodies    
PITRM1 (Pitrilysin Metallopeptidase 1): PITRM1 antibodies PITRM1 ELISA Kits PITRM1 Proteins
PMPCA - Peptidase (Mitochondrial Processing) alpha:      
STOM - Stomatin: STOM antibodies STOM ELISA Kits STOM Proteins
Slc25a21 - Solute Carrier Family 25 (Mitochondrial Oxodicarboxylate Carrier), Member 21: Slc25a21 antibodies   Slc25a21 Proteins
TARS2 - threonyl-tRNA Synthetase 2, Mitochondrial (Putative): TARS2 antibodies TARS2 ELISA Kits  
FASTKD5 - FAST Kinase Domains 5: FASTKD5 antibodies    
ETFA - Electron-Transfer-Flavoprotein, alpha Polypeptide: ETFA antibodies ETFA ELISA Kits ETFA Proteins
C20orf4 - Chromosome 20 Open Reading Frame 4: C20orf4 antibodies   C20orf4 Proteins
TUBGCP3 (Tubulin, gamma Complex Associated Protein 3): TUBGCP3 antibodies   TUBGCP3 Proteins
ATP6V1A - ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A: ATP6V1A antibodies ATP6V1A ELISA Kits ATP6V1A Proteins
AKAP8L - A Kinase (PRKA) Anchor Protein 8-Like: AKAP8L antibodies AKAP8L ELISA Kits AKAP8L Proteins
SLC30A7 - Solute Carrier Family 30 (Zinc Transporter), Member 7: SLC30A7 antibodies SLC30A7 ELISA Kits SLC30A7 Proteins
SLC30A9 - Solute Carrier Family 30 (Zinc Transporter), Member 9: SLC30A9 antibodies    
BZW2 (Basic Leucine Zipper and W2 Domains 2): BZW2 antibodies   BZW2 Proteins
ACADM - Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain: ACADM antibodies ACADM ELISA Kits ACADM Proteins
RTN4 - Reticulon 4: RTN4 antibodies RTN4 ELISA Kits RTN4 Proteins
ADCK4 (AarF Domain Containing Kinase 4): ADCK4 antibodies   ADCK4 Proteins

NSP1

Antigens in this category:
PKP2 - Plakophilin 2: PKP2 antibodies PKP2 ELISA Kits  
POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit)): POLA2 antibodies POLA2 ELISA Kits POLA2 Proteins
POLA1 - DNA Polymerase alpha: POLA1 antibodies   POLA1 Proteins
PRIM2 - Primase, DNA, Polypeptide 2 (58kDa): PRIM2 antibodies PRIM2 ELISA Kits PRIM2 Proteins
PRIM1 - Primase, DNA, Polypeptide 1 (49kDa): PRIM1 antibodies   PRIM1 Proteins
GLT25D1 (Glycosyltransferase 25 Domain Containing 1): GLT25D1 antibodies GLT25D1 ELISA Kits  

NSP2

Antigens in this category:
KIAA1033 - KIAA1033: KIAA1033 antibodies    
RAP1GDS1 (RAP1, GTP-GDP Dissociation Stimulator 1): RAP1GDS1 antibodies RAP1GDS1 ELISA Kits RAP1GDS1 Proteins
GIGYF2 (GRB10 Interacting GYF Protein 2): GIGYF2 antibodies   GIGYF2 Proteins
SLC27A2 - Solute Carrier Family 27 (Fatty Acid Transporter), Member 2: SLC27A2 antibodies   SLC27A2 Proteins
EIF4E2 - Eukaryotic Translation Initiation Factor 4E Family Member 2: EIF4E2 antibodies   EIF4E2 Proteins
POR (P450 (Cytochrome) Oxidoreductase): POR antibodies POR ELISA Kits POR Proteins
FKBP15 (FK506 Binding Protein 15, 133kDa): FKBP15 antibodies   FKBP15 Proteins

NSP4

Antigens in this category:
TIMM10 (Translocase of Inner Mitochondrial Membrane 10 Homolog (Yeast)): TIMM10 antibodies TIMM10 ELISA Kits TIMM10 Proteins
C19ORF52 - TIMM29: C19ORF52 antibodies    
FXC1 - Fracture Callus 1 Homolog (Rat): FXC1 antibodies   FXC1 Proteins
DNAJC11 (DnaJ (Hsp40) Homolog, Subfamily C, Member 11): DNAJC11 antibodies   DNAJC11 Proteins
ALG11 - Asparagine-Linked Glycosylation 11, alpha-1,2-Mannosyltransferase Homolog (Yeast): ALG11 antibodies   ALG11 Proteins
IDE - Insulin-Degrading Enzyme: IDE antibodies IDE ELISA Kits IDE Proteins
TIMM9 - Translocase of Inner Mitochondrial Membrane 9 Homolog (Yeast): TIMM9 antibodies TIMM9 ELISA Kits TIMM9 Proteins
NUP210 (Nucleoporin 210kDa): NUP210 antibodies   NUP210 Proteins

NSP5

Antigens in this category:
HDAC2 - Histone Deacetylase 2: HDAC2 antibodies HDAC2 ELISA Kits HDAC2 Proteins

NSP5_C145A

Antigens in this category:
TRMT1 - tRNA Methyltransferase 1 Homolog (S. Cerevisiae): TRMT1 antibodies   TRMT1 Proteins
GPX1 - Glutathione Peroxidase 1: GPX1 antibodies GPX1 ELISA Kits GPX1 Proteins

NSP6

Antigens in this category:
ATP5L (ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit G): ATP5L antibodies ATP5L ELISA Kits ATP5L Proteins
SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1): SIGMAR1 antibodies SIGMAR1 ELISA Kits SIGMAR1 Proteins
ATP13A3 (ATPase Type 13A3): ATP13A3 antibodies    
ATP6AP1 - ATPase, H+ Transporting, Lysosomal Accessory Protein 1: ATP6AP1 antibodies   ATP6AP1 Proteins

NSP7

Antigens in this category:
FAM162A - Family with Sequence Similarity 162, Member A: FAM162A antibodies   FAM162A Proteins
RAB10 (RAB10, Member RAS Oncogene Family): RAB10 antibodies RAB10 ELISA Kits RAB10 Proteins
NAT14 - N-Acetyltransferase 14 (GCN5-Related, Putative): NAT14 antibodies   NAT14 Proteins
NDUFAF2 - NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2: NDUFAF2 antibodies   NDUFAF2 Proteins
SELS - Selenoprotein S: SELS antibodies SELS ELISA Kits SELS Proteins
TOR1AIP1 (Torsin A Interacting Protein 1): TOR1AIP1 antibodies   TOR1AIP1 Proteins
QSOX2 (Quiescin Q6 Sulfhydryl Oxidase 2): QSOX2 antibodies    
SCCPDH - Saccharopine Dehydrogenase (Putative): SCCPDH antibodies SCCPDH ELISA Kits SCCPDH Proteins
GNG5 (G Protein gamma 5): GNG5 antibodies   GNG5 Proteins
LMAN2 - Lectin, Mannose-Binding 2: LMAN2 antibodies LMAN2 ELISA Kits LMAN2 Proteins
MOGS - Mannosyl-Oligosaccharide Glucosidase: MOGS antibodies   MOGS Proteins
DCAKD (dephospho-CoA Kinase Domain Containing): DCAKD antibodies DCAKD ELISA Kits DCAKD Proteins
CYB5B - Cytochrome B5 Type B (Outer Mitochondrial Membrane): CYB5B antibodies CYB5B ELISA Kits CYB5B Proteins
HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1): HS2ST1 antibodies HS2ST1 ELISA Kits HS2ST1 Proteins
COMT (Catechol-O-Methyltransferase): COMT antibodies COMT ELISA Kits COMT Proteins
Acsl3 (Acyl-CoA Synthetase Long-Chain Family Member 3): Acsl3 antibodies   Acsl3 Proteins
AGPS (Alkylglycerone Phosphate Synthase): AGPS antibodies AGPS ELISA Kits AGPS Proteins
RAB2A - RAB2A, Member RAS Oncogene Family: RAB2A antibodies   RAB2A Proteins
GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1): GNB1 antibodies GNB1 ELISA Kits GNB1 Proteins
PTGES2 (Prostaglandin E Synthase 2): PTGES2 antibodies PTGES2 ELISA Kits PTGES2 Proteins
rala (Ras-related Protein Ral-A): rala antibodies rala ELISA Kits rala Proteins
RHOA (Ras Homolog Gene Family, Member A): RHOA antibodies RHOA ELISA Kits RHOA Proteins
RAB7A - RAB7A, Member RAS Oncogene Family: RAB7A antibodies RAB7A ELISA Kits RAB7A Proteins
Rab5c (RAB5C, Member RAS Oncogene Family): Rab5c antibodies Rab5c ELISA Kits Rab5c Proteins
RAB1A (RAB1A, Member RAS Oncogene Family): RAB1A antibodies RAB1A ELISA Kits RAB1A Proteins
RAB18 (RAB18, Member RAS Oncogene Family): RAB18 antibodies   RAB18 Proteins
RAB14 (RAB14, Member RAS Oncogene Family): RAB14 antibodies RAB14 ELISA Kits RAB14 Proteins
RAB8A (RAB8A, Member RAS Oncogene Family): RAB8A antibodies RAB8A ELISA Kits RAB8A Proteins
MOSC1 - MOCO Sulphurase C-terminal Domain Containing 1: MOSC1 antibodies MOSC1 ELISA Kits MOSC1 Proteins
DNAJC19 - DnaJ (Hsp40) Homolog, Subfamily C, Member 19: DNAJC19 antibodies DNAJC19 ELISA Kits DNAJC19 Proteins
CYB5R3 - Cytochrome B5 Reductase 3: CYB5R3 antibodies CYB5R3 ELISA Kits CYB5R3 Proteins
SCARB1 (Scavenger Receptor Class B, Member 1): SCARB1 antibodies SCARB1 ELISA Kits SCARB1 Proteins

NSP8

Antigens in this category:
NGDN - Neuroguidin, EIF4E Binding Protein: NGDN antibodies NGDN ELISA Kits NGDN Proteins
MRPS2 (Mitochondrial Ribosomal Protein S2): MRPS2 antibodies   MRPS2 Proteins
NOL10 (Nucleolar Protein 10):      
MPHOSPH10 - M-Phase phosphoprotein 10 (U3 Small Nucleolar Ribonucleoprotein): MPHOSPH10 antibodies MPHOSPH10 ELISA Kits MPHOSPH10 Proteins
CCDC86 - Coiled-Coil Domain Containing 86: CCDC86 antibodies CCDC86 ELISA Kits CCDC86 Proteins
SEPSECS (Sep (O-phosphoserine) tRNA:Sec (Selenocysteine) tRNA Synthase): SEPSECS antibodies SEPSECS ELISA Kits SEPSECS Proteins
MRPS5 (Mitochondrial Ribosomal Protein S5): MRPS5 antibodies   MRPS5 Proteins
NARS2 - Asparaginyl-tRNA Synthetase 2, Mitochondrial (Putative): NARS2 antibodies   NARS2 Proteins
MRPS27 - Mitochondrial Ribosomal Protein S27: MRPS27 antibodies   MRPS27 Proteins
MRPS25 - Mitochondrial Ribosomal Protein S25: MRPS25 antibodies MRPS25 ELISA Kits MRPS25 Proteins
DDX10 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 10): DDX10 antibodies DDX10 ELISA Kits DDX10 Proteins
SRP19 (Signal Recognition Particle 19kDa): SRP19 antibodies   SRP19 Proteins
SRP54 (Signal Recognition Particle 54kDa): SRP54 antibodies   SRP54 Proteins
SRP72 (Signal Recognition Particle 72kDa): SRP72 antibodies    
EXOSC5 (Exosome Component 5): EXOSC5 antibodies   EXOSC5 Proteins
WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1): WHSC1 antibodies   WHSC1 Proteins
MEPCE (Methylphosphate Capping Enzyme): MEPCE antibodies MEPCE ELISA Kits MEPCE Proteins
LARP7 (La Ribonucleoprotein Domain Family, Member 7): LARP7 antibodies LARP7 ELISA Kits LARP7 Proteins
HECTD1 (HECT Domain Containing 1): HECTD1 antibodies   HECTD1 Proteins
EXOSC2 - Exosome Component 2: EXOSC2 antibodies EXOSC2 ELISA Kits EXOSC2 Proteins
EXOSC8 - Exosome Component 8: EXOSC8 antibodies   EXOSC8 Proteins
EXOSC3 - Exosome Component 3: EXOSC3 antibodies   EXOSC3 Proteins
ATE1 (Arginyltransferase 1): ATE1 antibodies ATE1 ELISA Kits ATE1 Proteins
AATF (Apoptosis Antagonizing Transcription Factor): AATF antibodies AATF ELISA Kits AATF Proteins

NSP9

Antigens in this category:
NUPL1 - Nucleoporin Like 1: NUPL1 antibodies NUPL1 ELISA Kits NUPL1 Proteins
SPG20 (Spastic Paraplegia 20 (Troyer Syndrome)): SPG20 antibodies   SPG20 Proteins
NUP54 - Nucleoporin 54kDa: NUP54 antibodies   NUP54 Proteins
NEK9 - NIMA (Never in Mitosis Gene A)- Related Kinase 9: NEK9 antibodies NEK9 ELISA Kits NEK9 Proteins
DCAF7 (DDB1 and CUL4 Associated Factor 7): DCAF7 antibodies   DCAF7 Proteins
GTF2F2 - General Transcription Factor IIF, Polypeptide 2, 30kDa: GTF2F2 antibodies   GTF2F2 Proteins
ZNF503 - Zinc Finger Protein 503: ZNF503 antibodies   ZNF503 Proteins
NUP88 - Nucleoporin 88kDa: NUP88 antibodies   NUP88 Proteins
MIB1 - Mindbomb E3 Ubiquitin Protein Ligase 1: MIB1 antibodies   MIB1 Proteins
NUP62 (Nucleoporin 62kDa): NUP62 antibodies NUP62 ELISA Kits NUP62 Proteins
MAT2B (Methionine Adenosyltransferase II, beta): MAT2B antibodies MAT2B ELISA Kits MAT2B Proteins
FBLN5 - Fibulin 5: FBLN5 antibodies FBLN5 ELISA Kits FBLN5 Proteins
FBN2 - Fibrillin 2: FBN2 antibodies FBN2 ELISA Kits FBN2 Proteins
FBN1 - Fibrillin 1: FBN1 antibodies FBN1 ELISA Kits FBN1 Proteins
EIF4H (Eukaryotic Translation Initiation Factor 4H): EIF4H antibodies   EIF4H Proteins
NUP214 (Nucleoporin 214kDa): NUP214 antibodies NUP214 ELISA Kits  

NSP10

Antigens in this category:
GRPEL1 - GrpE-Like 1, Mitochondrial: GRPEL1 antibodies   GRPEL1 Proteins
ERGIC1 - Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) 1: ERGIC1 antibodies ERGIC1 ELISA Kits ERGIC1 Proteins
GFER (Growth Factor, Augmenter of Liver Regeneration): GFER antibodies GFER ELISA Kits GFER Proteins
AP2A2 (Adaptor-Related Protein Complex 2, alpha 2 Subunit): AP2A2 antibodies    
AP2M1 - Adaptor-Related Protein Complex 2, mu 1 Subunit: AP2M1 antibodies AP2M1 ELISA Kits AP2M1 Proteins

NSP11

Antigens in this category:
TBCA - Tubulin Folding Cofactor A: TBCA antibodies   TBCA Proteins

Nsp12

Antigens in this category:
SBNO1 - Strawberry Notch Homolog 1: SBNO1 antibodies   SBNO1 Proteins
LARP4B (La Ribonucleoprotein Domain Family, Member 4B): LARP4B antibodies    
SLU7 (SLU7 Splicing Factor Homolog (S. Cerevisiae)): SLU7 antibodies   SLU7 Proteins
USP54 (Ubiquitin Specific Peptidase 54): USP54 antibodies    
RBM41 (RNA Binding Motif Protein 41): RBM41 antibodies   RBM41 Proteins
UBAP2 - Ubiquitin Associated Protein 2: UBAP2 antibodies UBAP2 ELISA Kits  
MYCBP2 (MYC Binding Protein 2): MYCBP2 antibodies    
RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1): RIPK1 antibodies RIPK1 ELISA Kits RIPK1 Proteins
PLEKHA5 (Pleckstrin Homology Domain Containing, Family A Member 5): PLEKHA5 antibodies    
PRRC2B (Proline-Rich Coiled-Coil 2B): PRRC2B antibodies    
TYSND1 - Trypsin Domain Containing 1: TYSND1 antibodies   TYSND1 Proteins
PPIL3 - Peptidylprolyl Isomerase (Cyclophilin)-Like 3: PPIL3 antibodies   PPIL3 Proteins
ZC3H7A (Zinc Finger CCCH-Type Containing 7A): ZC3H7A antibodies    
UBAP2L (Ubiquitin Associated Protein 2-Like): UBAP2L antibodies    
AKAP8 (A Kinase (PRKA) Anchor Protein 8): AKAP8 antibodies   AKAP8 Proteins
Znf318 - Zinc Finger Protein 318: Znf318 antibodies    
TCF12 (Transcription Factor 12): TCF12 antibodies   TCF12 Proteins
PDZD11 - PDZ Domain Containing 11: PDZD11 antibodies   PDZD11 Proteins
CRTC3 (CREB Regulated Transcription Coactivator 3): CRTC3 antibodies CRTC3 ELISA Kits CRTC3 Proteins
BCKDK (Branched Chain Ketoacid Dehydrogenase Kinase): BCKDK antibodies BCKDK ELISA Kits BCKDK Proteins

NSP13

Antigens in this category:
CLIP4 (CAP-GLY Domain Containing Linker Protein Family, Member 4): CLIP4 antibodies   CLIP4 Proteins
C1ORF50 (Chromosome 1 Open Reading Frame 50): C1ORF50 antibodies    
NINL (Ninein-Like): NINL antibodies    
GCC1 - GRIP and Coiled-Coil Domain Containing 1: GCC1 antibodies GCC1 ELISA Kits GCC1 Proteins
PDE4DIP - phosphodiesterase 4D Interacting Protein: PDE4DIP antibodies PDE4DIP ELISA Kits  
TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila)): TLE1 antibodies   TLE1 Proteins
TLE3 (Transducin-Like Enhancer of Split 3 (E(sp1) Homolog, Drosophila)): TLE3 antibodies    
CNTRL - Centriolin: CNTRL antibodies CNTRL ELISA Kits  
HOOK1 - Hook Homolog 1 (Drosophila): HOOK1 antibodies   HOOK1 Proteins
ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1): ERC1 antibodies ERC1 ELISA Kits ERC1 Proteins
FYCO1 (FYVE and Coiled-Coil Domain Containing 1): FYCO1 antibodies FYCO1 ELISA Kits FYCO1 Proteins
JAKMIP1 (Janus Kinase and Microtubule Interacting Protein 1): JAKMIP1 antibodies   JAKMIP1 Proteins
CEP68 (Centrosomal Protein 68kDa): CEP68 antibodies CEP68 ELISA Kits CEP68 Proteins
MIPOL1 (Mirror-Image Polydactyly 1): MIPOL1 antibodies   MIPOL1 Proteins
USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3)): USP13 antibodies   USP13 Proteins
PRKACA (Protein Kinase A, alpha): PRKACA antibodies PRKACA ELISA Kits PRKACA Proteins
GCC2 - GRIP and Coiled-Coil Domain Containing 2: GCC2 antibodies    
CIT (Citron (Rho-Interacting, serine/threonine Kinase 21)): CIT antibodies   CIT Proteins
CCDC46 - Coiled-Coil Domain Containing 46: CCDC46 antibodies   CCDC46 Proteins
PRKAR2B - Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta: PRKAR2B antibodies PRKAR2B ELISA Kits PRKAR2B Proteins
PRKAR2A - Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha: PRKAR2A antibodies   PRKAR2A Proteins
GOLGA3 - Golgin A3: GOLGA3 antibodies   GOLGA3 Proteins
GOLGA2 - Golgin A2: GOLGA2 antibodies   GOLGA2 Proteins
GOLGB1 - Golgin B1: GOLGB1 antibodies    
TBK1 - TANK-Binding Kinase 1: TBK1 antibodies TBK1 ELISA Kits TBK1 Proteins
CEP250 (Centrosomal Protein 250kDa): CEP250 antibodies    
CEP135 (Centrosomal Protein 135kDa): CEP135 antibodies CEP135 ELISA Kits  
NIN - Ninein (GSK3B Interacting Protein): NIN antibodies   NIN Proteins
AKAP9 (A Kinase (PRKA) Anchor Protein (Yotiao) 9): AKAP9 antibodies    
PKA - Protein Kinase A: PKA antibodies PKA ELISA Kits  
TBKBP1 - TBK1 Binding Protein 1: TBKBP1 antibodies TBKBP1 ELISA Kits TBKBP1 Proteins
RDX - Radixin: RDX antibodies RDX ELISA Kits RDX Proteins
PCNT - Pericentrin: PCNT antibodies PCNT ELISA Kits  
GORASP1 - Golgi Reassembly Stacking Protein 1, 65kDa: GORASP1 antibodies   GORASP1 Proteins
GRIPAP1 - GRIP1 Associated Protein 1: GRIPAP1 antibodies   GRIPAP1 Proteins
FGFR1OP - FGFR1 Oncogene Partner: FGFR1OP antibodies FGFR1OP ELISA Kits FGFR1OP Proteins
CEP350 (Centrosomal Protein 350kDa): CEP350 antibodies    
CENPF (Centromere Protein F): CENPF antibodies CENPF ELISA Kits  
CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2): CDK5RAP2 antibodies    
AES (Amino-terminal Enhancer of Split): AES antibodies AES ELISA Kits AES Proteins
HSBP1 (Heat Shock Factor Binding Protein 1): HSBP1 antibodies HSBP1 ELISA Kits HSBP1 Proteins

NSP14

Antigens in this category:
GLA (Galactosidase, alpha): GLA antibodies GLA ELISA Kits GLA Proteins
IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2): IMPDH2 antibodies IMPDH2 ELISA Kits IMPDH2 Proteins
SIRT5 - Sirtuin 5: SIRT5 antibodies SIRT5 ELISA Kits SIRT5 Proteins

NSP15

Antigens in this category:
ARF6 - ADP-Ribosylation Factor 6: ARF6 antibodies ARF6 ELISA Kits ARF6 Proteins
NUTF2 - Nuclear Transport Factor 2: NUTF2 antibodies   NUTF2 Proteins
RNF41 (Ring Finger Protein 41): RNF41 antibodies   RNF41 Proteins

ORF3b

Antigens in this category:
STOML2 (Stomatin (EPB72)-Like 2): STOML2 antibodies STOML2 ELISA Kits STOML2 Proteins

ORF3a

Antigens in this category:
VPS39 (Vacuolar Protein Sorting 39 Homolog (S. Cerevisiae)): VPS39 antibodies   VPS39 Proteins
TRIM59 (Tripartite Motif Containing 59): TRIM59 antibodies   TRIM59 Proteins
VPS11 - Vacuolar Protein Sorting 11 Homolog (S. Cerevisiae): VPS11 antibodies   VPS11 Proteins
SUN2 (Sad1 and UNC84 Domain Containing 2): SUN2 antibodies   SUN2 Proteins
HMOX1 - Heme Oxygenase (Decycling) 1: HMOX1 antibodies HMOX1 ELISA Kits HMOX1 Proteins
ARL6IP6 - ADP-Ribosylation-Like Factor 6 Interacting Protein 6: ARL6IP6 antibodies ARL6IP6 ELISA Kits ARL6IP6 Proteins
ALG5 (Asparagine-Linked Glycosylation 5, Dolichyl-Phosphate beta-Glucosyltransferase Homolog (S. Cerevisiae)): ALG5 antibodies   ALG5 Proteins
CLCC1 - Chloride Channel CLIC-Like 1: CLCC1 antibodies CLCC1 ELISA Kits CLCC1 Proteins

ORF6

Antigens in this category:
MTCH1 (Mitochondrial Carrier 1): MTCH1 antibodies MTCH1 ELISA Kits MTCH1 Proteins
RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe)): RAE1 antibodies   RAE1 Proteins
NUP98 - Nucleoporin 98kDa: NUP98 antibodies NUP98 ELISA Kits NUP98 Proteins

ORF7a

Antigens in this category:
HEATR3 (HEAT Repeat Containing 3): HEATR3 antibodies    
MDN1 - MDN1, Midasin Homolog (Yeast):      

ORF8

Antigens in this category:
CISD3 (CDGSH Iron Sulfur Domain 3):   CISD3 ELISA Kits  
KDELC2 (KDEL (Lys-Asp-Glu-Leu) Containing 2): KDELC2 antibodies   KDELC2 Proteins
KDELC1 - KDEL (Lys-Asp-Glu-Leu) Containing 1: KDELC1 antibodies KDELC1 ELISA Kits KDELC1 Proteins
PUSL1 (Pseudouridylate Synthase-Like 1): PUSL1 antibodies   PUSL1 Proteins
FOXRED2 - FAD-Dependent Oxidoreductase Domain Containing 2: FOXRED2 antibodies   FOXRED2 Proteins
PLD3 - Phospholipase D family member 3: PLD3 antibodies PLD3 ELISA Kits PLD3 Proteins
TM2D3 - TM2 Domain Containing 3: TM2D3 antibodies   TM2D3 Proteins
HS6ST2 (Heparan Sulfate 6-O-Sulfotransferase 2): HS6ST2 antibodies HS6ST2 ELISA Kits HS6ST2 Proteins
PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2): PLOD2 antibodies PLOD2 ELISA Kits PLOD2 Proteins
TOR1A - Torsin Family 1, Member A (Torsin A): TOR1A antibodies   TOR1A Proteins
NPX1 - Neuronal Pentraxin 1: NPX1 antibodies NPX1 ELISA Kits NPX1 Proteins
ERO1LB - ERO1-Like beta (S. Cerevisiae): ERO1LB antibodies   ERO1LB Proteins
KIAA0090 - KIAA0090: KIAA0090 antibodies   KIAA0090 Proteins
NPC2 (Niemann-Pick Disease, Type C2): NPC2 antibodies NPC2 ELISA Kits NPC2 Proteins
GGH - gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase): GGH antibodies GGH ELISA Kits GGH Proteins
ERLEC1 - Endoplasmic Reticulum Lectin 1: ERLEC1 antibodies ERLEC1 ELISA Kits ERLEC1 Proteins
OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin): OS9 antibodies   OS9 Proteins
INHBE - Inhibin, beta E: INHBE antibodies INHBE ELISA Kits INHBE Proteins
EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3): EDEM3 antibodies   EDEM3 Proteins
ADAM9 (ADAM Metallopeptidase Domain 9): ADAM9 antibodies ADAM9 ELISA Kits ADAM9 Proteins
UGT2 - UDP-Glucose Glycoprotein Glucosyltransferase 2: UGT2 antibodies   UGT2 Proteins
ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1): ADAMTS1 antibodies ADAMTS1 ELISA Kits ADAMTS1 Proteins
FBXL12 (F-Box and Leucine-Rich Repeat Protein 12): FBXL12 antibodies FBXL12 ELISA Kits FBXL12 Proteins
DNMT1 - DNA (Cytosine-5)-Methyltransferase 1: DNMT1 antibodies DNMT1 ELISA Kits DNMT1 Proteins
NGLY1 - N-Glycanase 1: NGLY1 antibodies NGLY1 ELISA Kits NGLY1 Proteins
ERP44 - Endoplasmic Reticulum Protein 44: ERP44 antibodies   ERP44 Proteins
CHPF (Chondroitin Polymerizing Factor): CHPF antibodies    
NEU1 (Sialidase 1 (Lysosomal Sialidase)): NEU1 antibodies NEU1 ELISA Kits NEU1 Proteins
POFUT1 (Protein O-Fucosyltransferase 1): POFUT1 antibodies POFUT1 ELISA Kits POFUT1 Proteins
PLEKHF2 - Pleckstrin Homology Domain Containing, Family F (With FYVE Domain) Member 2: PLEKHF2 antibodies   PLEKHF2 Proteins
ITGB1 - Integrin beta 1: ITGB1 antibodies ITGB1 ELISA Kits ITGB1 Proteins
HYOU1 (Hypoxia Up Regulated 1): HYOU1 antibodies HYOU1 ELISA Kits HYOU1 Proteins
PLAT (Plasminogen Activator, Tissue): PLAT antibodies PLAT ELISA Kits PLAT Proteins
STC2 - Stanniocalcin 2: STC2 antibodies STC2 ELISA Kits STC2 Proteins
SMOC1 (SPARC Related Modular Calcium Binding 1): SMOC1 antibodies SMOC1 ELISA Kits SMOC1 Proteins
SDF2 (Stromal Cell Derived Factor 2): SDF2 antibodies SDF2 ELISA Kits SDF2 Proteins
PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6): PCSK6 antibodies    
MFGE8 (Milk Fat Globule-EGF Factor 8 Protein): MFGE8 antibodies MFGE8 ELISA Kits MFGE8 Proteins
LOX (Lysyl Oxidase): LOX antibodies LOX ELISA Kits LOX Proteins
IL17RA (Interleukin 17 Receptor A): IL17RA antibodies IL17RA ELISA Kits IL17RA Proteins
GDF15 (Growth Differentiation Factor 15): GDF15 antibodies GDF15 ELISA Kits GDF15 Proteins
FKBP10 - FK506 Binding Protein 10, 65 KDa: FKBP10 antibodies   FKBP10 Proteins
FKBP7 - FK506 Binding Protein 7: FKBP7 antibodies   FKBP7 Proteins
COL6A1 - Collagen, Type VI, alpha 1: COL6A1 antibodies COL6A1 ELISA Kits COL6A1 Proteins
PVR - Poliovirus Receptor: PVR antibodies PVR ELISA Kits PVR Proteins
SIL1 (SIL1 Homolog, Endoplasmic Reticulum Chaperone (S. Cerevisiae)): SIL1 antibodies SIL1 ELISA Kits SIL1 Proteins

ORF9b

Antigens in this category:
SLC9A3R1 - Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1: SLC9A3R1 antibodies   SLC9A3R1 Proteins
TOMM70A - Translocase of Outer Mitochondrial Membrane 70 Homolog A (S. Cerevisiae): TOMM70A antibodies TOMM70A ELISA Kits TOMM70A Proteins
DPH5 (DPH5 Homolog (S. Cerevisiae)): DPH5 antibodies   DPH5 Proteins
CHMP2A (Charged Multivesicular Body Protein 2A): CHMP2A antibodies   CHMP2A Proteins
MARK3 - MAP/microtubule Affinity-Regulating Kinase 3: MARK3 antibodies MARK3 ELISA Kits MARK3 Proteins
MARK2 - MAP/microtubule Affinity-Regulating Kinase 2: MARK2 antibodies   MARK2 Proteins
MARK1 (MAP/microtubule Affinity-Regulating Kinase 1): MARK1 antibodies MARK1 ELISA Kits MARK1 Proteins
BAG5 (BCL2-Associated Athanogene 5): BAG5 antibodies   BAG5 Proteins
DCTPP1 (DCTP Pyrophosphatase 1): DCTPP1 antibodies DCTPP1 ELISA Kits DCTPP1 Proteins
PTBP2 - Polypyrimidine Tract Binding Protein 2: PTBP2 antibodies   PTBP2 Proteins
CDSE1 (Cold Shock Domain Containing E1, RNA-Binding): CDSE1 antibodies CDSE1 ELISA Kits CDSE1 Proteins

ORF9c

Antigens in this category:
TMEM39B (Transmembrane Protein 39B): TMEM39B antibodies   TMEM39B Proteins
PIGS - Phosphatidylinositol Glycan Anchor Biosynthesis, Class S: PIGS antibodies   PIGS Proteins
TAPT1 (Transmembrane Anterior Posterior Transformation 1): TAPT1 antibodies    
SLC30A6 (Solute Carrier Family 30 (Zinc Transporter), Member 6): SLC30A6 antibodies SLC30A6 ELISA Kits SLC30A6 Proteins
TMED5 (Transmembrane Emp24 Protein Transport Domain Containing 5): TMED5 antibodies   TMED5 Proteins
NLRX1 (NLR Family Member X1): NLRX1 antibodies NLRX1 ELISA Kits  
NDUFB9 - NADH Dehydrogenase (Ubiquinone) 1 beta Subcomplex, 9, 22kDa: NDUFB9 antibodies   NDUFB9 Proteins
TMEM97 (Transmembrane Protein 97): TMEM97 antibodies TMEM97 ELISA Kits TMEM97 Proteins
UBXN8 - UBX Domain Protein 8: UBXN8 antibodies   UBXN8 Proteins
FAR2 - Fatty Acyl CoA Reductase 2: FAR2 antibodies FAR2 ELISA Kits  
ERMP1 (Endoplasmic Reticulum Metallopeptidase 1): ERMP1 antibodies ERMP1 ELISA Kits ERMP1 Proteins
F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1): F2RL1 antibodies F2RL1 ELISA Kits F2RL1 Proteins
GHITM - Growth Hormone Inducible Transmembrane Protein: GHITM antibodies GHITM ELISA Kits GHITM Proteins
FAM134C (Family with Sequence Similarity 134, Member C): FAM134C antibodies    
GPAA1 - GPI Anchor Attachment Protein 1: GPAA1 antibodies GPAA1 ELISA Kits GPAA1 Proteins
ACAD9 - Acyl-CoA Dehydrogenase Family, Member 9: ACAD9 antibodies    
ALG8 (Asparagine-Linked Glycosylation 8, alpha-1,3-Glucosyltransferase Homolog (S. Cerevisiae)): ALG8 antibodies   ALG8 Proteins
BCS1L - BCS1-Like (S. Cerevisiae): BCS1L antibodies BCS1L ELISA Kits BCS1L Proteins
NDUFAF1 - NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 1: NDUFAF1 antibodies   NDUFAF1 Proteins
DPY19L1 (Dpy-19-Like 1 (C. Elegans)): DPY19L1 antibodies    
ECSIT (ECSIT Homolog (Drosophila)): ECSIT antibodies ECSIT ELISA Kits ECSIT Proteins
ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1): ABCC1 antibodies ABCC1 ELISA Kits ABCC1 Proteins
SCAP - SREBF chaperone: SCAP antibodies   SCAP Proteins
PIGO (Phosphatidylinositol Glycan Anchor Biosynthesis, Class O): PIGO antibodies   PIGO Proteins
WFS1 - Wolfram Syndrome 1: WFS1 antibodies WFS1 ELISA Kits WFS1 Proteins
NDFIP2 (Nedd4 Family Interacting Protein 2): NDFIP2 antibodies   NDFIP2 Proteins

ORF10

Antigens in this category:
ZYG11B - Zyg-11 Family Member B, Cell Cycle Regulator: ZYG11B antibodies   ZYG11B Proteins
TIMM8B (Translocase of Inner Mitochondrial Membrane 8 Homolog B (Yeast)): TIMM8B antibodies TIMM8B ELISA Kits TIMM8B Proteins
MAP7D1 (MAP7 Domain Containing 1): MAP7D1 antibodies    
THTPA - Thiamine Triphosphatase: THTPA antibodies THTPA ELISA Kits THTPA Proteins
RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase): RBX1 antibodies   RBX1 Proteins
TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C)): TCEB1 antibodies   TCEB1 Proteins
TCEB2 - Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B): TCEB2 antibodies TCEB2 ELISA Kits TCEB2 Proteins
PPT1 (Palmitoyl-Protein Thioesterase 1): PPT1 antibodies PPT1 ELISA Kits PPT1 Proteins
CUL2 - Cullin 2: CUL2 antibodies CUL2 ELISA Kits CUL2 Proteins