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Serotonin Receptor 1A antibody (N-Term)

HTR1A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN184237
  • Target See all Serotonin Receptor 1A (HTR1A) Antibodies
    Serotonin Receptor 1A (HTR1A)
    Binding Specificity
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 42
    • 26
    • 26
    • 1
    • 1
    Human
    Host
    • 36
    • 5
    • 2
    Rabbit
    Clonality
    • 39
    • 4
    Polyclonal
    Conjugate
    • 23
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Serotonin Receptor 1A antibody is un-conjugated
    Application
    • 34
    • 18
    • 13
    • 13
    • 13
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    GQGNNTTSPP APFETGGNTT GISDVTVSYQ VITSLLLGTL IFCAVLGNAC
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against HTR1A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human HTR1A
    Top Product
    Discover our top product HTR1A Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 422 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Adeosun, Albert, Austin, Iyo: "17?-estradiol-induced regulation of the novel 5-HT1A-related transcription factors NUDR and Freud-1 in SH SY5Y cells." in: Cellular and molecular neurobiology, Vol. 32, Issue 4, pp. 517-21, (2012) (PubMed).

    Szewczyk, Albert, Rogaeva, Fitzgibbon, May, Rajkowska, Miguel-Hidalgo, Stockmeier, Woolverton, Kyle, Wang, Austin: "Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depression." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 13, Issue 8, pp. 1089-101, (2010) (PubMed).

    Szewczyk, Albert, Burns, Czesak, Overholser, Jurjus, Meltzer, Konick, Dieter, Herbst, May, Rajkowska, Stockmeier, Austin: "Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 2, pp. 155-68, (2009) (PubMed).

    Cordeaux, Pasupathy, Bacon, Charnock-Jones, Smith: "Characterization of serotonin receptors in pregnant human myometrium." in: The Journal of pharmacology and experimental therapeutics, Vol. 328, Issue 3, pp. 682-91, (2009) (PubMed).

    Iyo, Kieran, Chandran, Albert, Wicks, Bissette, Austin: "Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress." in: Neuroscience, Vol. 163, Issue 4, pp. 1119-27, (2009) (PubMed).

  • Target
    Serotonin Receptor 1A (HTR1A)
    Alternative Name
    HTR1A (HTR1A Products)
    Synonyms
    5-HT-dro2A antibody, 5-HT1ADro antibody, 5-HT[1A]Dro antibody, 5-HT[[1ADro]] antibody, 5-HT[[1A]] antibody, 5-HT[[1A]]DRO antibody, 5HT-R2A antibody, 5HT-dro2A antibody, 5HT-drp[[2A]] antibody, 5HT1A antibody, 5HT[[1ADro]] antibody, 5htdro2a antibody, CG16720 antibody, DRO2A antibody, Dm5HTdro2A antibody, Dmel\\CG16720 antibody, d5-HT1A antibody, 5htr1a antibody, htr1a antibody, HTR1A antibody, Htr1a antibody, 5-Ht1a antibody, Gpcr18 antibody, 5-HT-1A antibody, 5-HT1A antibody, 5HT1a antibody, ADRB2RL1 antibody, ADRBRL1 antibody, G-21 antibody, PFMCD antibody, RAT5HT1A antibody, 5ht1a antibody, adrb2rl1 antibody, adrbrl1 antibody, htr1a-A antibody, 5-hydroxytryptamine (serotonin) receptor 1A antibody, 5-hydroxytryptamine receptor 1A antibody, 5-hydroxytryptamine (serotonin) receptor 1A a antibody, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog antibody, 5-HT1A antibody, HTR1A antibody, htr1aa antibody, Htr1a antibody, htr1a.L antibody
    Background
    This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity.
    Alias Symbols: 5HT1a, 5-HT1A, ADRBRL1, ADRB2RL1
    Protein Interaction Partner: UBC, RHOA, GABBR2, GPR26, S1PR1, S1PR3, HTR1D, HTR1B, GNAI3, HTR1A,
    Protein Size: 422
    Molecular Weight
    46 kDa
    Gene ID
    3350
    NCBI Accession
    NM_000524, NP_000515
    UniProt
    P08908
    Pathways
    JAK-STAT Signaling, Synaptic Membrane, Feeding Behaviour
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