Serotonin Receptor 1A (HTR1A) (N-Term) antibody

Details for Product No. ABIN184237
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Antigen
Synonyms
5-HT-dro2A, 5-HT1ADro, 5-HT[1A]Dro, 5-HT[[1ADro]], 5-HT[[1A]], 5-HT[[1A]]DRO, 5HT-R2A, 5HT-dro2A, 5HT-drp[[2A]], 5HT1A, 5HT[[1ADro]], 5htdro2a, CG16720, DRO2A, Dm5HTdro2A, Dmel\\CG16720, d5-HT1A, 5htr ... show more
5-HT-dro2A, 5-HT1ADro, 5-HT[1A]Dro, 5-HT[[1ADro]], 5-HT[[1A]], 5-HT[[1A]]DRO, 5HT-R2A, 5HT-dro2A, 5HT-drp[[2A]], 5HT1A, 5HT[[1ADro]], 5htdro2a, CG16720, DRO2A, Dm5HTdro2A, Dmel\\CG16720, d5-HT1A, 5htr1a, htr1a, HTR1A, Htr1a, 5-Ht1a, Gpcr18, 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD, RAT5HT1A, 5ht1a, adrb2rl1, adrbrl1, htr1a-A show less
Epitope
N-Term
(8), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(29), (25), (20)
Host
Rabbit
(38), (5), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1)
Application
Western Blotting (WB)
(39), (20), (8), (4), (4), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
Options
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Catalog No. ABIN184237
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Immunogen Synthetic peptide directed towards the N terminal of human HTR1A
Sequence GQGNNTTSPP APFETGGNTT GISDVTVSYQ VITSLLLGTL IFCAVLGNAC
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against HTR1A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name HTR1A
Background This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity.
Molecular Weight 46 kDa
Gene ID 3350
NCBI Accession NM_000524, NP_000515
UniProt P08908
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 422 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibody anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibody
anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibody (2) Host: Rabbit
Target Name: HTR1A
Sample Tissue: Jurkat Whole Cell lysates
Antibody Dilution: 1.0 µg/mL
anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibody (3) Host: Rabbit
Target Name: HTR1A
Sample Tissue: Jurkat
Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1.0 µg/mL Peptide Concentration: 1.0 µg/mL Lysate Quantity: 241 µg/laneGel Concentration: 12 %
anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibody (4) HTR1A Antibody - N-terminal region (AVARP13041_P050) validated by WB using primary cultured neurons
Background publications Czesak, Lemonde, Peterson et al.: "Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 6, pp. 1864-71, 2006 (PubMed).

Validation Images
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