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Details for Product No. ABIN184638

Dual Specificity Phosphatase 1 (DUSP1) (C-Term) antibody

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Antigen
Synonyms HVH1, MKP1, CL100, MKP-1, PTPN10, Mkp1, 3CH134, Ptpn16, U19515, erp, mkp-1, DUSP1, cb269, sb:cb269, zgc:55920, id:ibd2586, wu:fd19g02, wu:fe50g09
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN184638
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence SYLQSPITTSPSC, from the C Terminus of the protein sequence according to NP_004408.1.
Cross-Reactivity Dog (Canine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Dual specificity protein phosphatase 1 (DUSP1/MKP-1)
Background Synonyms: DUSP1, dual specificity phosphatase 1, HVH1, CL100, MKP-1, PTPN10, serine/threonine specific protein phosphatase, MKP1
Gene ID 1843, 19252
NCBI Accession NP_004408.1
Research Area Signaling
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx. 40 kDa band observed in Human lysates of HeLa (calculated MW of 39.3 kDa according to NP_004408.1). Recommended concentration: 0.3-1 µg/mL. An anonymous customer found positive results in WB on Mouse microglia (BV2 cells). An anonymous customer found positive results in WB on Rat primary microglia. An anonymous customer found positive results in WB on Rat spinal cord homogenate.
IHC: In paraffin embedded Human Prostate shows strong cytoplasm staining of secretory cells in the glands. Recommended concentration: 3-5 µg/mL.
Restrictions For Research Use only
Format Liquid
Concentration 100µg specific antibody in 200µl
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Alessi, Smythe, Keyse: "The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts." in: Oncogene, Vol. 8, Issue 7, pp. 2015-20, 1993 (PubMed).

Alternatives for antigen "Dual Specificity Phosphatase 1 (DUSP1)", type "Antibodies"
Hosts (77), (11), (4)
Reactivities (91), (56), (38), (38), (36), (32), (24)
Applications (46), (40), (38), (24), (12), (4), (2), (1), (1)
Conjugates (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Epitopes (25), (17), (13), (6), (4), (4), (2), (1), (1)
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