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Details for Product No. ABIN184810

Interferon Regulatory Factor 2 (IRF2) (C-Term) antibody

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Synonyms IRF-2, 9830146E22Rik, AI646973, Irf-2, irf2b, zgc:103451
»Alternatives C-Term
»Alternatives Human, Mouse (Murine)
Clonality Polyclonal
Methode Type Peptide ELISA
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN184810
Quantity 100 µg
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence KTSDITQARVKSC, from the C Terminus of the protein sequence according to NP_002190.2.
Cross-Reactivity Rat (Rattus), Dog (Canine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name IRF2
Background Synonyms: IRF2, interferon regulatory factor 2, DKFZp686F0244, IRF-2
Gene ID 3660, 16363
NCBI Accession NP_002190.2
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Innate Immunity, Cytokines
Application Notes ELISA: antibody detection limit dilution 1:2000.
Western blot: Approx 48 kDa band observed in lysates of cell line Jurkat (calculated MW of 39.3 kDa according to NP_002190.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Li et al, Invest Ophthalmol Vis Sci. 1999 Apr,40(5):976-82., PMID: 10102295. In transfected HEK293 transiently expressing IRF2 bands of approx. 40 kDa and 45 kDa are observed. These bands are not observed in the non-transfected HEK293. Recommended concentration: 1-3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Product cited in: Liljeroos, Vuolteenaho, Rounioja et al.: "Bacterial ligand of TLR2 signals Stat activation via induction of IRF1/2 and interferon-alpha production." in: Cellular signalling, Vol. 20, Issue 10, pp. 1873-81, 2008 (PubMed).

Harada, Kitagawa, Tanaka et al.: "Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2." in: Science (New York, N.Y.), Vol. 259, Issue 5097, pp. 971-4, 1993 (PubMed).

Alternatives for antigen "Interferon Regulatory Factor 2 (IRF2)", type "Antibodies"
Hosts (28), (15), (7)
Reactivities (48), (19), (14), (3), (3), (2), (1), (1), (1)
Applications (45), (23), (12), (10), (6), (3), (1), (1), (1)
Epitopes (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)