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Details for Product No. ABIN185152

Par-6 Partitioning Defective 6 Homolog alpha (C. Elegans) (PARD6A) (C-Term) antibody

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Antigen
Synonyms Par6a, Par-6a, Par6, Par-6, Par6c, TAX40, Tip-40, PAR6alpha, 0710008C04Rik, 2610010A15Rik, PAR6, PAR6C, PAR-6A, TIP-40, PARD6A
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN185152
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Availability Ships within 5 Business Days
Immunogen Peptide with sequence C-GSRIRGDGSGFSL, from the C Terminus of the protein sequence according to NP_058644.1, NP_001032358.1.
Specificity This antibody is expected to recognise both reported isoforms (NP_058644.1, NP_001032358.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name PAR6alpha / PARD6A
Background Synonyms: PARD6A, PAR6alpha, PAR-6, TAX40, PAR-6A, TIP-40, par-6 partitioning defective 6 homolog alpha (C.elegans), Tax interaction protein 40, par-6 (partitioning defective 6, C.elegans) homolog alpha, PAR6, PAR6C, Tax-interacting protein 40, par-6 partitioning defective 6 homolog alpha, partitioning defective-6 homolog alpha, partitioning-defective protein 6
Gene ID 50855
NCBI Accession NP_058644.1, NP_001032358.1
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: Preliminary experiments gave no signal but low background in Human Brain and Pancreas extracts at up to 1 µg/mL.
IHC: In paraffin embedded Human Pancreas, shows strong cytoplasmic staining in rare cells of intralobular ducts. Recommended concentration: 10 µg/mL. Also tested in paraffin embedded Human Heart where it shows speckled staining on myocardial fibres in transverse section. Recommended concentration: 5-10 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Johansson, Driessens, Aspenström: "The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1." in: Journal of cell science, Vol. 113 ( Pt 18), pp. 3267-75, 2000 (PubMed).

Alternatives for antigen "Par-6 Partitioning Defective 6 Homolog alpha (C. Elegans) (PARD6A)", type "Antibodies"
Hosts (46), (7), (2)
Reactivities (40), (17), (12), (12), (10), (1), (1)
Applications (37), (24), (12), (10), (6), (3), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (15), (7), (3), (3), (1), (1)
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