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PARD6A Products

(Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

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This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured PARD6A Categories

PARD6A Antibodies

High quality antibodies with extensive validation data.

PARD6A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PARD6A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, FACS
Validations
  • (3)
Cat. No. ABIN185152
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN526360
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF
Validations
  • (2)
Cat. No. ABIN7162663
Quantity 100 μg
Datasheet Datasheet

Recommended PARD6A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313999
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314001
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3085394
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PARD6A products

Campos, Qiu, Gomero, Wakefield, Horner, Brutkowski, Han, Solecki, Frase, Bongiovanni, dAzzo: "Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier." in: Nature communications, Vol. 7, pp. 11876, (2016) (PubMed).

Lechuga, Baranwal, Ivanov: "Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 308, Issue 9, pp. G745-56, (2015) (PubMed).

Johansson, Driessens, Aspenström: "The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1." in: Journal of cell science, Vol. 113 ( Pt 18), pp. 3267-75, (2000) (PubMed).

Synonyms and alternative names related to PARD6A

par-6 partitioning defective 6 homolog alpha (C. elegans) (PARD6A), par-6 family cell polarity regulator alpha (PARD6A), par-6 family cell polarity regulator alpha (Pard6a), Partitioning defective protein 6 (par-6), 0710008C04Rik, 2610010A15Rik, Par-6, Par-6a, PAR-6A, Par6, PAR6, Par6a, PAR6alpha, Par6c, PAR6C, PARD6A, TAX40, Tip-40, TIP-40

Protein level used designations for PARD6A

  • par-6 partitioning defective 6 homolog alpha (C. elegans)
  • partitioning defective 6 homolog alpha
  • PAR-6 alpha
  • PAR-6A
  • Tax interaction protein 40
  • partitioning defective protein 6A
  • Tax-interacting protein 40
  • par-6 partitioning defective 6 homolog alpha
  • partitioning defective-6 homolog alpha
  • partitioning-defective protein 6
  • tax interaction protein 40
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