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Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C) antibody

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Synonyms 2010016F01Rik, harmonin, AIE-75, DFNB18, DFNB18A, NY-CO-37, NY-CO-38, PDZ-45, PDZ-73, PDZ-73/NY-CO-38, PDZ73, PDZD7C, ush1cpst
(64), (10), (7), (3), (1), (1), (1), (1), (1)
(39), (16), (9)
(5), (5), (5), (3), (3), (3)
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
(49), (45), (21), (6), (3), (2), (2), (1)
Pubmed 1 reference available
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Quantity 100 μg
Shipping to United States ( )
Availability Available
Blocking Peptide Blocking peptide for this product available: ABIN370094
Specificity This antibody is expected to recognize both reported isoforms (NP_005700.2 and NP_710142.1). Human, Mouse, Rat 652 aa
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name USH1C / Harmonin (USH1C Antibody Abstract)
Background All names and symbols: USH1C, AIE-75, DFNB18, PDZ-45, PDZ-73, HARMONIN, NY-CO-37, NY-CO-38, PDZ-73/NY-CO-38, Usher syndrome 1C (autosomal recessive, severe), harmonin, PDZ-73 protein, ush1cpst, deafness, autosomal recessive 18. Official Symbol: USH1C. RefSeq number(s): NP_005700.2, NP_710142.1
Gene ID 10083, 72088, 308596
Application Notes Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Approx 75kDa band observed in lysates of cell line HEK293 (calculated MW of 62.2kDa according to NP_005700.2). Recommended concentration: 0.1-0.3µg/ml. Immunohistochemistry: In paraffin embedded Human Kidney, shows diffuse cytopasmic staining in epithelial cells of renal tubules. Recommended concentration, 10µg/ml. (IHC data have been obtained with EB06287 from previous batch).
Restrictions For Research Use only
Format Liquid
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
Image no. 1 for anti-Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C) antibody (ABIN185190) ABIN185190 (0.1 ug/ml) staining of HEK293 lysate (35 ug protein in RIPA buffer). Pri...
Immunohistochemistry (IHC) image for anti-Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C) antibody (ABIN185190) ABIN185190 (10 ug/ml) staining of paraffin embedded Human Kidney. Microwaved antigen ...
Background publications Verpy, Leibovici, Zwaenepoel et al.: "A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C." in: Nature genetics, Vol. 26, Issue 1, pp. 51-5, 2000 (PubMed).

Catalog No. ABIN185190
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