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Details for Product No. ABIN185339

CD274 Molecule (CD274) (C-Term) antibody

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Antigen
Synonyms B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7h1, Pdl1, Pdcd1l1, Pdcd1lg1, A530045L16Rik, RGD1566211
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN185339
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence CKKQSDTHLEET, from the C Terminus of the protein sequence according to NP_054862.1.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name CD274 / PD-L1
Background Synonyms: CD274 antigen, PD-L1, PDCD1LG1, B7-H, B7H1, PDL1, PDCD1L1, programmed cell death 1 ligand 1, PDL1, HGNC:17635, CD274, CD274 molecule, MGC142294, MGC142296
Gene ID 29126
NCBI Accession NP_054862.1
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 35 kDa band observed in Human Heart lysates (calculated MW of 33.3 kDa according to NP_054862.1). Recommended concentration: 0.3-1.0 µg/mL.
IHC: In paraffin embedded Human Skel,etal Muscle shows staining of the striated muscular fibres. Recommended concentration: 4-6 µg/mL. Data obtained with a previous batch.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Product cited in: Chen, Li, Meng et al.: "Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 1, pp. 101-8, 2012 (PubMed).

Thompson, Gillett, Cheville et al.: "Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 49, pp. 17174-9, 2004 (PubMed).

Alternatives for antigen "CD274 Molecule (CD274)", type "Antibodies"
Hosts (71), (35), (34), (7)
Reactivities (93), (90), (51), (20), (20), (1)
Applications (81), (55), (32), (21), (20), (18), (7), (5), (5), (2), (2), (1), (1)
Conjugates (17), (10), (8), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Epitopes (10), (5), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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