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PD-L1 Products

(CD274 (PD-L1))

Categories

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

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Featured PD-L1 Categories

PD-L1 Antibodies

High quality antibodies with extensive validation data.

PD-L1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PD-L1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PD-L1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, ELISA, IF
Validations
  • (1)
  • (11)
Cat. No. ABIN185339
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC, ELISA, IF
Validations
  • (9)
Cat. No. ABIN7164674
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC, ELISA, ICC, Neut
Validations
  • (6)
Cat. No. ABIN7193243
Quantity 0.1 mg
Datasheet Datasheet

Recommended PD-L1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (18)
  • (5)
Cat. No. ABIN6574208
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6974711
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6999545
Quantity 96 tests
Datasheet Datasheet

Recommended PD-L1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7275430
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7275429
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7275434
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PD-L1 products

Faruk, Ibrahim, Aminu, Adamu, Abdullahi, Suleiman, Rafindadi, Mohammed, Iliyasu, Idoko, Saidu, Randawa, Musa, Ntekim, Shah, Abubakar, Adoke, Manko, Awasum: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." in: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).

Kim, Lee, Kim, Suh, Nam, Bang, Jin, Oh, Kim, Kim, Oh: "The prognostic role of soluble transforming growth factor-β and its correlation with soluble programmed death-ligand 1 in biliary tract cancer." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 41, Issue 2, pp. 388-395, (2021) (PubMed).

Ye, Yuan, Yue, Rubin, Chen: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." in: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).

Li, Ren, Zhao, Lou: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." in: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).

Liu, Weng, Xu, Wang, Liu, Zhang, Guo, Dang, Xing, Lu, Han: "Computational Recognition and Clinical Verification of TGF-β-Derived miRNA Signature With Potential Implications in Prognosis and Immunotherapy of Intrahepatic Cholangiocarcinoma." in: Frontiers in oncology, Vol. 11, pp. 757919, (2021) (PubMed).

Kim, Kim, Kim, Kim, Kim: "Differential Expression and Clinicopathological Significance of HER2, Indoleamine 2,3-Dioxygenase and PD-L1 in Urothelial Carcinoma of the Bladder." in: Journal of clinical medicine, Vol. 9, Issue 5, (2020) (PubMed).

Qin, Wang, Ye, Li, Chen, Wang, Qin, Zhang, Li, Long, Hu, Shi, Li, Zhang, Zhai, Tang, Kang, Lan, Xie, Lu, Deng: "NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer." in: Nature communications, Vol. 11, Issue 1, pp. 1669, (2020) (PubMed).

Gondhowiardjo, Handoko, Adham, Rachmadi, Kodrat, Tobing, Haryoga, Dwiyono, Kristian, Mayang Permata: "Tumor microenvironment predicts local tumor extensiveness in PD-L1 positive nasopharyngeal cancer." in: PLoS ONE, Vol. 15, Issue 3, pp. e0230449, (2020) (PubMed).

Liu, Wen, Wu, Hu, Wang, Bao, Wang, Wang, Zhou, Wei, Shen, Zhang: "MicroRNA-200a induces immunosuppression by promoting PTEN-mediated PD-L1 upregulation in osteosarcoma." in: Aging, Vol. 12, Issue 2, pp. 1213-1236, (2020) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Synonyms and alternative names related to PD-L1

CD274 molecule (CD274), CD274 antigen (Cd274), programmed cell death 1 ligand 2 (PDCD1LG2), CD274 molecule (Cd274), A530045L16Rik, B7-H, B7H1, B7h1, PD-L1, PDCD1L1, Pdcd1l1, PDCD1LG1, Pdcd1lg1, PDL1, Pdl1, RGD1566211

Protein level used designations for PD-L1

  • B7 homolog 1
  • CD274 antigen
  • PDCD1 ligand 1
  • programmed cell death 1 ligand 1
  • programmed death ligand 1
  • CD274 molecule
  • programmed cell death ligand 1
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