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Details for Product No. ABIN185513

Klotho (KL) (Internal Region) antibody

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Antigen
Synonyms alpha-kl, KL, Kitl, LOC100223456
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN185513
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Availability Ships within 5 Business Days
Immunogen Peptide with sequence C-KRDDAKYMYYLKK, from the internal region of the protein sequence according to NP_004786.2, NP_710150.1.
Specificity This antibody is expected to recognise both reported isoforms (NP_004786.2, NP_710150.1).
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Klotho
Background Synonyms: KL, klotho
Gene ID 9365
NCBI Accession NP_004786.2, NP_710150.1
Research Area Metabolism
Application Notes ELISA: antibody detection limit dilution 1:4000.
Western blot: Preliminary experiments in human brain, duodenum, placenta and prostate lysates gave no specific signal but low background (at antibody concentration up to 1 µg/mL).
IHC: In paraffin embedded Human Breast shows cytoplasm staining in luminal epithelial cells of ducts, while Human Placenta shows membranous staining. Recommended concentration: 4-6 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Kurosu, Yamamoto, Clark et al.: "Suppression of aging in mice by the hormone Klotho." in: Science (New York, N.Y.), Vol. 309, Issue 5742, pp. 1829-33, 2005 (PubMed).

Alternatives for antigen "Klotho (KL)", type "Antibodies"
Hosts (50), (8), (4)
Reactivities (46), (39), (26), (17), (17), (17)
Applications (43), (27), (17), (11), (10), (10), (2), (2), (2), (1), (1)
Conjugates (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (7), (5), (4), (2), (2), (1)
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