Klotho (KL) (Internal Region) antibody

Details for Product No. ABIN185513
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms KL, Kitl, LOC100223456, alpha-kl
Epitope
Internal Region
(12), (10), (8), (7), (5), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(55), (41), (29), (17), (17), (17)
Host
Goat
(60), (6), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
(49), (28), (14), (12), (11), (10), (6), (4)
Pubmed 1 reference available
Quantity 100 µg
Options
Shipping to United States (Change)
Availability Available
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN185513
374.27 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide with sequence C-KRDDAKYMYYLKK, from the internal region of the protein sequence according to NP_004786.2, NP_710150.1.
Specificity This antibody is expected to recognise both reported isoforms (NP_004786.2, NP_710150.1).
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Klotho
Background Synonyms: KL, klotho
Gene ID 9365
NCBI Accession NP_710150, NP_004786
Research Area Metabolism
Application Notes ELISA: antibody detection limit dilution 1:4000.
Western blot: Preliminary experiments in human brain, duodenum, placenta and prostate lysates gave no specific signal but low background (at antibody concentration up to 1 µg/mL).
IHC: In paraffin embedded Human Breast shows cytoplasm staining in luminal epithelial cells of ducts, while Human Placenta shows membranous staining. Recommended concentration: 4-6 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
General Kurosu, Yamamoto, Clark et al.: "Suppression of aging in mice by the hormone Klotho." in: Science (New York, N.Y.), Vol. 309, Issue 5742, pp. 1829-33, 2005 (PubMed).

Validation Images
Did you look for something else?
back to top