CD63 antibody

Catalog No. ABIN187370

Product Details anti-CD63 Antibody

Target: CD63

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD63 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Specificity: The antibody reacts with CD63 antigen (Melanoma 1 antigen), a glycoprotein of 40-60 kDa belonging to tetraspans family (TM4SF). CD63 is intracellular lysosomal/endosomal/ granule protein that is translocated to cell surface upon activation of platelets, endothelial cells, and granulocytes (activation marker). CD63 is also expressed on monocytes/ macrophages and endothelium. Its cellular function has not been exactly elucidated. CD63 is thought to be associated with the early stages of melanoma tumor progression (in regulation of motility and adhesion of melanoma cells).

Clone: MEM-259

Isotype: IgG1

Application Details

Application Notes: Immunoprecipitation Western blotting: non-reducing conditions. Flow Cytometry: For detection of activated platelets, neutrophils and basophils. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 ml at 1 mg/ml in PBS pH 7.4 with 15 mM sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD63

Target: CD63

Alternative Name: CD63 (CD63 Products)