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Details for Product No. ABIN190770

Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) (Internal Region) antibody

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Synonyms CCHLA2, Cacna2, DHSCCA, CACNA2, CCHL2A, CACNL2A, Ca(v)alpha2delta1, Cchl2a, CACNA2D1, DKFZp469K2211
»Alternatives Internal Region
»Alternatives Human
Clonality Polyclonal
»Alternatives Un-conjugated
Methode Type Peptide ELISA
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN190770
Quantity 100 µg
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-QEIFNKYNKDKKVR, from the internal region of the protein sequence according to NP_000713.2.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Grade Verified
Alternative Name CACNA2D1
Background Synonyms: CACNA2D1, calcium channel, voltage-dependent, alpha 2/delta subunit 1, CACNA2, CACNL2A, CCHL2A, MHS3, H_DJ0560O14.1, WUGSC:H_DJ0560O14.1, calcium channel, L type, alpha 2 polypeptide, dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit
Gene ID 781, 12293, 25399
NCBI Accession NP_000713.2
Application Notes ELISA: antibody detection limit dilution 1:16000.
Western blot: Approx 140 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 123 kDa according to NP_000713.2). Recommended concentration: 0.03-0.1 µg/mL. Customer found it not suitable on Mouse and Rat protein.
Restrictions For Research Use only
Format Liquid
Concentration 100µg/200µl
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Product cited in: Neely, Hess, Costigan et al.: "A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene." in: Cell, Vol. 143, Issue 4, pp. 628-38, 2010 (PubMed).

Hullin, Matthes, von Vietinghoff et al.: "Increased expression of the auxiliary beta2-subunit of ventricular L-type Ca2+ channels leads to single-channel activity characteristic of heart failure." in: PLoS ONE, Vol. 2, Issue 3, pp. e292, 2007 (PubMed).

Alternatives for antigen "Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1)", type "Antibodies"
Hosts (41), (5), (2)
Reactivities (42), (32), (30), (20), (19), (18), (3), (1), (1)
Applications (33), (18), (17), (10), (9), (6), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (3), (2), (1), (1)