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CD40 antibody (N-Term)

CD40 Reactivity: Human FACS Host: Mouse Monoclonal HI40a unconjugated

Catalog No. ABIN206912

Datasheet as PDF

Target See all CD40 Antibodies

CD40
Binding Specificity
18

17

16

14

13

10

9

5

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reactivity
181

103

19

19

8

6

6

5

4

3

2

2

2

2

1
Human
Host
106

95

47

5

3

1
Mouse
Compatible Secondaries
Clonality
165

83

7
Monoclonal
Conjugate
128

23

23

15

11

5

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD40 antibody is un-conjugated
Application
160

87

61

50

36

28

23

20

17

14

13

12

5

4

4

4

4

4

4

3

3

3

2

2

2

1
Flow Cytometry (FACS)

Specificity

Recognizes CD40 (BP50), a 48 KD type I single chain transmembrane glycoprotein expressed on normal and neoplastic B cells, but not on terminally differentiated plasma cells. CD40 antigen is also present on Hodgkin's and Reed-Sternberg cells, follicular dendritic cells, some macrophages, basal epithelial cells and endothelial cells

Purification

Protein A purified

Immunogen

Type of Immunogen: Native protein

Clone

HI40a

Isotype

IgG1

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anti-CD40 (CD40) (AA 26-187) antibody
CD40 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) antibody
CD40 Reactivity: Human FACS, IHC, IF, StM, DNA Mic Host: Mouse Monoclonal C40-1605 unconjugated

anti-CD40 (CD40) (C-Term) antibody
CD40 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) (AA 21-193) antibody
CD40 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 4C3B8 unconjugated

anti-CD40 (CD40) (AA 29-107) antibody
CD40 Reactivity: Human FACS, ELISA, IHC, StM, Coat Host: Mouse Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reactivity: Human FACS, IHC, St Host: Mouse Monoclonal 5C3 unconjugated

anti-CD40 (CD40) antibody
CD40 Reactivity: Human FACS Host: Mouse Monoclonal HI40a unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reactivity: Human FACS Host: Mouse Monoclonal HI40a FITC

anti-CD40 (CD40) antibody
CD40 Reactivity: Human FACS, IHC, IP, Act Host: Rabbit Chimeric G28-5 unconjugated Recombinant Antibody

Application Notes

Approved: Flo

Usage: Flow Cytometry: The purified antibody is effective for indirect immunofluorescence staining of human cells by flow cytometry analysis using 1 μg/mL. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Azide free PBS, preserved by filter sterilization, approx,  pH 7.4.

Preservative

Azide free

Handling Advice

avoid freeze thaw cycles.

Storage

4 °C,-20 °C

Storage Comment

Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Target

CD40

Alternative Name

CD40 (CD40 Products)

Background

Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

Gene ID

958

UniProt

P25942

Pathways

NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints