Chromogranin A antibody
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- Target See all Chromogranin A (CHGA) Antibodies
- Chromogranin A (CHGA)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Chromogranin A antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC)
- Purification
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding CGA
- Clone
- NJ-5C9
- Isotype
- IgG1
- Top Product
- Discover our top product CHGA Primary Antibody
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- Application Notes
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
ELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Restrictions
- For Research Use only
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- Buffer
- PBS, pH 7.2
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C
- Storage Comment
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- Chromogranin A (CHGA)
- Alternative Name
- Chromogranin A (CHGA Products)
- Background
- Chromogranin A (CgA) is a 49 kDa protein which is a member of the granin/secretogranin family of acidic glycoproteins. It is specifically expressed in all endocrine and neuroendocrine cells and plays multiple roles in the process of regulated secretion of peptide hormones and neurotransmitters. Owing to its over-expression in several tumors of neuroendocrine origin, CgA is of diagnostic value in classical endocrine, in hormone-negative and in neuroendocrine tumors.
- UniProt
- P10645
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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