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Activin Receptor Type I (ACRV1) (Internal Region) antibody

Details for Product No. ABIN238620, Supplier: Login to see
Antigen
  • ALK2
  • ActR-I
  • ActRIA
  • Acvr
  • Acvrlk2
  • Alk-2
  • Alk8
  • D330013D15Rik
  • SKR1
  • Tsk7L
  • ACTRI
  • ACVR1A
  • ACVRLK2
  • FOP
  • TSRI
  • ActR-IA
Epitope
Internal Region
58
41
20
15
15
14
12
9
4
4
4
3
3
3
3
2
2
2
2
2
2
2
1
1
1
Reactivity
Human
137
43
12
7
4
2
2
2
1
1
1
1
1
1
1
1
Host
Goat
120
22
5
1
Clonality
Polyclonal
Conjugate
Un-conjugated
13
9
7
7
7
7
Methode Type
Peptide ELISA
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
128
88
61
24
3
3
2
1
Supplier
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Immunogen Peptide with sequence C-RKFKRRNQERLNPRD, from the internal region of the protein sequence according to NP_001096.1.
Blocking Peptide Blocking peptide for this product available: ABIN369779
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name ACVR1 (ACRV1 Antibody Abstract)
Background Synonyms: ACVR1, activin A receptor, type I, ACTRI, ACVRLK2, ALK2, FOP, SKR1, activin A receptor, type II-like kinase 2, activin A type I receptor, hydroxyalkyl-protein kinase
Gene ID 90
NCBI Accession NP_001096
Pathways
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Approx 60 kDa band observed in Human Umbilical Cord lysates (calculated MW of 57.2 kDa according to NP_001096.1). Recommended concentration: 0.3-1 µg/mL.
IHC: In paraffin embedded Human Testis shows preferential staining of cytoplasm in primary spermatocytes. Recommended concentration: 4-6 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-Activin Receptor Type I (ACRV1) (Internal Region) antibody (ABIN238620) ABIN238620 (0.3µg/ml) staining of Human Umbilical Cord lysate (35µg protein in RIPA b...
Background publications Shore, Xu, Feldman et al.: "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva." in: Nature genetics, Vol. 38, Issue 5, pp. 525-7, 2006 (PubMed).