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Details for Product No. ABIN238620

Activin Receptor Type I (ACRV1) (Internal Region) antibody

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Antigen
Synonyms FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2, Acvr, Alk8, Alk-2, Tsk7L, ActR-I, ActRIA, Acvrlk2, D330013D15Rik, ActR-IA
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN238620
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Availability Ships within 5 Business Days
Immunogen Peptide with sequence C-RKFKRRNQERLNPRD, from the internal region of the protein sequence according to NP_001096.1.
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name ACVR1
Background Synonyms: ACVR1, activin A receptor, type I, ACTRI, ACVRLK2, ALK2, FOP, SKR1, activin A receptor, type II-like kinase 2, activin A type I receptor, hydroxyalkyl-protein kinase
Gene ID 90
NCBI Accession NP_001096.1
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Approx 60 kDa band observed in Human Umbilical Cord lysates (calculated MW of 57.2 kDa according to NP_001096.1). Recommended concentration: 0.3-1 µg/mL.
IHC: In paraffin embedded Human Testis shows preferential staining of cytoplasm in primary spermatocytes. Recommended concentration: 4-6 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Shore, Xu, Feldman et al.: "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva." in: Nature genetics, Vol. 38, Issue 5, pp. 525-7, 2006 (PubMed).

Alternatives for antigen "Activin Receptor Type I (ACRV1)", type "Antibodies"
Hosts (42), (5), (3), (1)
Reactivities (43), (24), (5), (3), (2), (1)
Applications (50), (19), (17), (14), (4), (4), (1)
Conjugates (4), (2), (1)
Epitopes (15), (7), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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