ACVR1 antibody (AA 20-125)

Catalog No. ABIN7143174

Product Details anti-ACVR1 Antibody

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Binding Specificity: AA 20-125

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Activin receptor type-1 protein (20-125AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ACVR1

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Alternative Name: ACVR1 (ACRV1 Products)

Synonyms: ACTRI antibody, ACVR1A antibody, ACVRLK2 antibody, ALK2 antibody, FOP antibody, SKR1 antibody, TSRI antibody, ActR-IA antibody, ActR-I antibody, ActRIA antibody, Acvr antibody, Acvrlk2 antibody, Alk-2 antibody, Alk8 antibody, D330013D15Rik antibody, Tsk7L antibody, actri antibody, acvr1 antibody, acvr1-a antibody, acvr1-b antibody, acvr1a antibody, acvrlk2 antibody, alk-2 antibody, alk2 antibody, alk8 antibody, fop antibody, sax antibody, skr1 antibody, tsri antibody, xALK-2 antibody, activin A receptor type 1 antibody, activin A receptor, type 1 antibody, activin A receptor type 1 S homeolog antibody, ACVR1 antibody, Acvr1 antibody, acvr1.S antibody

Background:

Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis .

Aliases: Activin A receptor type I antibody, Activin A receptor type II like kinase 2 antibody, Activin receptor type I antibody, Activin receptor type-1 antibody, Activin receptor-like kinase 2 antibody, ACTR-I antibody, ACTRI antibody, Acvr1 antibody, ACVR1_HUMAN antibody, ACVR1A antibody, ACVRLK2 antibody, ALK 2 antibody, ALK-2 antibody, ALK2 antibody, FOP antibody, Hydroxyalkyl protein kinase antibody, Serine/threonine-protein kinase receptor R1 antibody, SKR1 antibody, TGF-B superfamily receptor type I antibody, TGFB superfamily receptor type I antibody, TSR-I antibody, TSRI antibody

UniProt: Q04771