Bestrophin 3 antibody
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- Target See all Bestrophin 3 (BEST3) Antibodies
- Bestrophin 3 (BEST3)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Bestrophin 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Characteristics
- Homo sapiens bestrophin 3 (BEST3), transcript variant 2
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human BEST3 (NP_689652) produced in HEK293T cell.
- Clone
- 2H3
- Isotype
- IgG1
- Top Product
- Discover our top product BEST3 Primary Antibody
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- Application Notes
- WB 1:2000, IF 1:100, FLOW 1:100
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- Bestrophin 3 (BEST3)
- Alternative Name
- BEST3 (BEST3 Products)
- Background
- BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD, MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738], Tsunenari et al., 2003 [PubMed 12907679]).
- Molecular Weight
- 50.8 kDa
- Gene ID
- 144453
- NCBI Accession
- NM_152439
- HGNC
- 144453
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