Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Bestrophin 3 Products

(Bestrophin 3 (BEST3))

Categories

BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD\; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]\; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured Bestrophin 3 Categories

Bestrophin 3 Antibodies

High quality antibodies with extensive validation data.

Bestrophin 3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Bestrophin 3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Bat, Cow, Dog, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN461699
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2784051
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (2)
Cat. No. ABIN1732303
Quantity 50 μg
Datasheet Datasheet

Recommended Bestrophin 3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6202077
Quantity 96 tests
Datasheet Datasheet

Recommended Bestrophin 3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089767
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123494
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123493
Quantity 0.25 mg
Datasheet Datasheet

Latest Publications for our Bestrophin 3 products

Golubinskaya, Elvin, Ebefors, Gustafsson, Mallard, Nyström, Nilsson: "Bestrophin-3 is differently expressed in normal and injured mouse glomerular podocytes." in: Acta physiologica (Oxford, England), Vol. 214, Issue 4, pp. 481-96, (2015) (PubMed).

Jiang, Liu, Ma, Tang, Zhou, Guan: "Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 5, pp. 556-65, (2013) (PubMed).

Wang, Yang, Zheng, Zhang, Tang, Wang, Du, Lv, Liu, Zhou, Guan: "Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation." in: Circulation, Vol. 125, Issue 5, pp. 697-707, (2012) (PubMed).

Lee, Chakraborty, Roussa, Wolff, Thévenod: "ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death in renal epithelial cells by reducing CHOP." in: Biochimica et biophysica acta, Vol. 1823, Issue 10, pp. 1864-76, (2012) (PubMed).

Broegger, Jacobsen, Secher Dam, Boedtkjer, Kold-Petersen, Pedersen, Aalkjaer, Matchkov: "Bestrophin is important for the rhythmic but not the tonic contraction in rat mesenteric small arteries." in: Cardiovascular research, Vol. 91, Issue 4, pp. 685-93, (2011) (PubMed).

Matchkov, Larsen, Bouzinova, Rojek, Boedtkjer, Golubinskaya, Pedersen, Aalkjaer, Nilsson: "Bestrophin-3 (vitelliform macular dystrophy 2-like 3 protein) is essential for the cGMP-dependent calcium-activated chloride conductance in vascular smooth muscle cells." in: Circulation research, Vol. 103, Issue 8, pp. 864-72, (2008) (PubMed).

Synonyms and alternative names related to Bestrophin 3

bestrophin 3 (BEST3), Bestrophin 3 (Best3), bestrophin 3 (best3), bestrophin 3 (Best3), best-3, BEST3, bestrophin-3, CG12327, dbest3, Dmel\\CG12327, mBest4, VMD2L3, Vmd2l3

Protein level used designations for Bestrophin 3

  • bestrophin 3
  • CG12327-PA
  • Best3-PA
  • bestrophin-3
  • bestrophin-3-like
  • vitelliform macular dystrophy 2-like 3
  • vitelliform macular dystrophy 2-like protein 3
You are here:
Support