CD86 antibody

Catalog No. ABIN2472673

Product Details anti-CD86 Antibody

Target: CD86

Reactivity: Cow, Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD86 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Clone IL-A190 recognises the bovine CD86 cell surface antigen, which is expressed by dendritic cells, activated macrophages and activated B cells. CD86 plays an important role in co-stimulation of T cells in the primary immune response.

Cross-Reactivity: Sheep (Ovine)

Characteristics: Purified IgG

Purification: Purified

Clone: IL-A190

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-CD86 antibody (ABIN2472673)

Langelaar, Hope, Rutten, Noordhuizen, van Eden, Koets: "Mycobacterium avium ssp. paratuberculosis recombinant heat shock protein 70 interaction with different bovine antigen-presenting cells." in: Scandinavian journal of immunology, Vol. 61, Issue 3, pp. 242-50, (2005) (PubMed).

Glew, Carr, Brackenbury, Hope, Charleston, Howard: "Differential effects of bovine viral diarrhoea virus on monocytes and dendritic cells." in: The Journal of general virology, Vol. 84, Issue Pt 7, pp. 1771-80, (2003) (PubMed).

Rhodes, Terry, Hope, Hewinson, Vordermeier: "1,25-dihydroxyvitamin D3 and development of tuberculosis in cattle." in: Clinical and diagnostic laboratory immunology, Vol. 10, Issue 6, pp. 1129-35, (2003) (PubMed).

Target Details for CD86

Target: CD86

Alternative Name: CD86 (CD86 Products)

UniProt: Q1JPC5

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation