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EGFR antibody (Extracellular Domain)

EGFR Reactivity: Human FACS, IHC (p), IP, IHC (fro) Host: Rat Monoclonal ICR10 unconjugated
Catalog No. ABIN2473405
  • Target See all EGFR Antibodies
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Binding Specificity
    • 39
    • 38
    • 31
    • 31
    • 29
    • 27
    • 27
    • 26
    • 24
    • 22
    • 19
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 11
    • 11
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Extracellular Domain
    Reactivity
    • 741
    • 296
    • 283
    • 25
    • 25
    • 24
    • 19
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 576
    • 167
    • 13
    • 13
    • 5
    • 1
    • 1
    Rat
    Clonality
    • 538
    • 233
    • 2
    Monoclonal
    Conjugate
    • 403
    • 58
    • 29
    • 22
    • 19
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EGFR antibody is un-conjugated
    Application
    • 530
    • 243
    • 145
    • 142
    • 126
    • 102
    • 97
    • 92
    • 82
    • 46
    • 37
    • 34
    • 33
    • 18
    • 11
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Characteristics
    Purified IgG
    Purification
    Purified
    Immunogen
    Extracellular domain of human EGF-receptor from head and neck carcinoma
    Clone
    ICR10
    Isotype
    IgG2a
    Top Product
    Discover our top product EGFR Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
  • Modjtahedi, Dean: "The receptor for EGF and its ligands - expression, prognostic value and target for therapy in cancer (review)." in: International journal of oncology, Vol. 4, Issue 2, pp. 277-96, (2011) (PubMed).

    Lottaz, Beier, Meyer, Kumar, Hermann, Schwarz, Junker, Oefner, Bogdahn, Wischhusen, Spang, Storch, Beier: "Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin." in: Cancer research, Vol. 70, Issue 5, pp. 2030-40, (2010) (PubMed).

  • Target
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Alternative Name
    EGF R (EGFR Products)
    Background
    Synonyms: EPIDERMAL GROWTH FACTOR RECEPTOR
    Gene ID
    1956
    UniProt
    P00533
    Pathways
    NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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