CD90.2 / Thy-1.2 antibody (APC)
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- Target See all CD90.2 / Thy-1.2 products
- CD90.2 / Thy-1.2
- Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD90.2 / Thy-1.2 antibody is conjugated to APC
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Application
- Flow Cytometry (FACS)
- Specificity
- The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Clone
- 30-H12
- Isotype
- IgG2b
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- Target
- CD90.2 / Thy-1.2
- Alternative Name
- CD90.2 (CD90.2 / Thy-1.2 Products)
- Background
- The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.2, expressed on thymocytes, mature T cells, epithelial cells, neurons, hematopoietic stem cells, and fibroblasts. CD90 is a membrane glycoprotein that regulates the adhesion and signal transduction in T lymphocytes, and the adhesion of thymocytes to thymic stroma.The interaction between 30-H12 and the antibody to the CD3/TCR complex upregulates thymocytes signal transduction and apoptosis and downregulates mature T cell proliferation. The 30-H12 antibody seems to be unable to cross-link with CD90.1.
- Gene ID
- 21838
- UniProt
- P01831
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