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CXCR4 antibody (APC)

CXCR4 Reactivity: Human FACS, ICFC Host: Mouse Monoclonal 12G5 APC
Catalog No. ABIN2658509
  • Target See all CXCR4 Antibodies
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Reactivity
    • 137
    • 83
    • 65
    • 21
    • 10
    • 10
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 118
    • 22
    • 10
    • 5
    • 1
    Mouse
    Clonality
    • 127
    • 29
    Monoclonal
    Conjugate
    • 95
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR4 antibody is conjugated to APC
    Application
    • 110
    • 50
    • 46
    • 36
    • 27
    • 26
    • 25
    • 25
    • 18
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
    Cross-Reactivity
    Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    Clone
    12G5
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Alternative Name
    CD184 (CXCR4 Products)
    Background
    CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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