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EGFR antibody (PE)

EGFR Reactivity: Human FACS Host: Mouse Monoclonal AY13 PE
Catalog No. ABIN2662713
  • Target See all EGFR Antibodies
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Reactivity
    • 748
    • 296
    • 283
    • 25
    • 25
    • 24
    • 19
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 580
    • 167
    • 14
    • 13
    • 5
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 542
    • 236
    • 2
    Monoclonal
    Conjugate
    • 410
    • 58
    • 29
    • 22
    • 19
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EGFR antibody is conjugated to PE
    Application
    • 535
    • 248
    • 149
    • 145
    • 126
    • 102
    • 98
    • 93
    • 82
    • 46
    • 37
    • 34
    • 34
    • 18
    • 11
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    AY13
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product EGFR Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Alternative Name
    EGFR (EGFR Products)
    Background
    Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein and member of the protein kinase superfamily that regulates cell growth and differentiation. EGFR binds EGF, TGF-α, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30, and vaccinia virus growth factor - all members of the EGF family. Ligand binding induces EGFR dimerization and autophosphorylation, initiating the MAPK, Akt, and JNK signaling pathways. EGFR is expressed by epithelial and endothelial cells and is frequently expressed by epithelial carcinomas.
    Pathways
    NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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