PVRL1 antibody (PE)

Catalog No. ABIN2662946

Product Details anti-PVRL1 Antibody (PE)

Target: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PVRL1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: R1-302

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for PVRL1

Target: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Alternative Name: CD111 (PVRL1 Products)

Background: CD111, known as poliovirus receptor related 1 protein (PRR1), Nectin-1 and HveC, is a 75 kD type I transmembrane glycoprotein. A member of the nectin family and Ig gene superfamily, CD111 is broadly expressed on endothelial cells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells. CD111 functions as one of the herpes simplex virus 1 (HSV-1) and HSV-2 receptors and is an adhesion molecule involved in the formation of cell junctions.

Pathways: Cell-Cell Junction Organization