CD51 antibody (PE)
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- Target See all CD51 (ITGAV) Antibodies
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD51 antibody is conjugated to PE
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Clone
- RMV-7
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ITGAV Primary Antibody
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anti-Integrin alpha V (ITGAV) antibody
ITGAV Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-Integrin alpha V (ITGAV) (C-Term) antibodyITGAV Reactivity: Human WB, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 560-744) antibodyITGAV Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 775-885) antibodyITGAV Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 71-322) antibodyITGAV Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 51-150) antibodyITGAV Reactivity: Human, Mouse WB, FACS, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) antibodyITGAV Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (C-Term) antibodyITGAV Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 1-1048) antibodyITGAV Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 1-1048) antibodyITGAV Reactivity: Human WB, PLA Host: Mouse Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Alternative Name
- CD51 (ITGAV Products)
- Background
- CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β 1, β3, β5 or β6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αv integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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