DLL1 antibody (PE)

Catalog No. ABIN2663684

Product Details anti-DLL1 Antibody (PE)

Target: DLL1 (delta-Like 1 (DLL1))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This DLL1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Characteristics: The Notch receptors and their ligands are highly conserved from invertebrates to mammals. The Delta-like 1 (DLL1) is one of the four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus.This translocation triggers a series of signaling process. Delta-like 1 is reported to be essential for the maintenance of marginal zone B cells in normal mice, and engagement of Notch 1 by DLL1 promotes differentiation of B lymphocytes to antibody-secreting cells.

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: HMD1-3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for DLL1

Target: DLL1 (delta-Like 1 (DLL1))

Alternative Name: DLL1 (DLL1 Products)

Pathways: Notch Signaling, Stem Cell Maintenance