-
- Target See all CD77 products
- CD77
- Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This CD77 antibody is un-conjugated
-
Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- 5B5
- Isotype
- IgM kappa
-
anti-CD77 antibody
Reactivity: Human FACS, ICC, IHC (fro) Host: Rat Monoclonal 38-13 unconjugated
anti-CD77 antibody (FITC)Reactivity: Human FACS Host: Rat Monoclonal 38-13 FITC
anti-CD77 antibody (PE)Reactivity: Human FACS Host: Rat Monoclonal 38-13 PE
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- Target
- CD77
- Abstract
- CD77 Products
- Background
- CD77, also known as Gb3S, A14GALT, A4GALT1, is a type II membrane protein. It was found specifically expressed on Burkitt's lymphoma cells and on a subset of germinal center B lymphocytes. CD77 has been described as a receptor for Shiga Toxin and Verotoxin 1 (VT1), which is produced by Shigella dysenteriae and some strains of E. coli . It is used as a marker for germinal center stage B-cells. CD19 has been reported as a ligand for D77 and their interaction functions in adhesion and signal transduction at a specific stage of B cell development. Studies have shown that cross-linking CD77 induces apoptosis in some B cell lines.
-
You are here:
